As regards the second problem offered to us by Redi, whether Xenogenesis obtains, side by side with Homogenesis,--whether, that is, there exist not only the ordinary living things, giving rise to offspring which run through the same cycle as themselves, but also others, producing offspring which are of a totally different character from themselves,-- the researches of two centuries have led to a different result. That the grubs found in galls are no product of the plants on which the galls grow, but are the result of the introduction of the eggs of insects into the substance of these plants, was made out by Vallisnieri, Réaumur, and others, before the end of the first half of the eighteenth century. The tapeworms, bladderworms, and flukes continued to be a stronghold of the advocates of Xenogenesis for a much longer period. Indeed, it is only within the last thirty years that the splendid patience of Von Siebold, Van Beneden, Leuckart, Küchenmeister, and other helminthologists, has succeeded in tracing every such parasite, often through the strangest wanderings and metamorphoses, to an egg derived from a parent, actually or potentially like itself; and the tendency of inquiries elsewhere has all been in the same direction. A plant may throw off bulbs, but these, sooner or later, give rise to seeds or spores, which develop into the original form. A polype may give rise to Medusae, or a pluteus to an Echinoderm, but the Medusa and the Echinoderm give rise to eggs which produce polypes or glutei, and they are therefore only stages in the cycle of life of the species. But if we turn to pathology, it offers us some remarkable approximations to true Xenogenesis. As I have already mentioned, it has been known since the time of Vallisnieri and of Réaumur, that galls in plants, and tumours in cattle, are caused by insects, which lay their eggs in those parts of the animal or vegetable frame of which these morbid structures are outgrowths. Again, it is a matter of familiar experience to everybody that mere pressure on the skin will give rise to a corn. Now the gall, the tumour, and the corn are parts of the living body, which have become, to a certain degree, independent and distinct organisms. Under the influence of certain external conditions, elements of the body, which should have developed in due subordination to its general plan, set up for themselves and apply the nourishment which they receive to their own purposes. From such innocent productions as corns and warts, there are all gradations to the serious tumours which, by their mere size and the mechanical obstruction they cause, destroy the organism out of which they are developed; while, finally, in those terrible structures known as cancers, the abnormal growth has acquired powers of reproduction and multiplication, and is only morphologically distinguishable from the parasitic worm, the life of which is neither more nor less closely bound up with that of the infested organism.