Such being the facts with respect to the Pébrine, what are the indications as to the method of preventing it? It is obvious that this depends upon the way in which the _Panhistophyton_ is generated. If it may be generated by Abiogenesis, or by Xenogenesis, within the silkworm or its moth, the extirpation of the disease must depend upon the prevention of the occurrence of the conditions under which this generation takes place. But if, on the other hand, the _Panhistophyton_ is an independent organism, which is no more generated by the silkworm than the mistletoe is generated by the apple-tree or the oak on which it grows, though it may need the silkworm for its development in the same way as the mistletoe needs the tree, then the indications are totally different. The sole thing to be done is to get rid of and keep away the germs of the _Panhistophyton_. As might be imagined, from the course of his previous investigations, M. Pasteur was led to believe that the latter was the right theory; and, guided by that theory, he has devised a method of extirpating the disease, which has proved to be completely successful wherever it has been properly carried out. There can be no reason, then, for doubting that, among insects, contagious and infectious diseases, of great malignity, are caused by minute organisms which are produced from pre-existing germs, or by homogenesis; and there is no reason, that I know of, for believing that what happens in insects may not take place in the highest animals. Indeed, there is already strong evidence that some diseases of an extremely malignant and fatal character to which man is subject, are as much the work of minute organisms as is the Pébrine. I refer for this evidence to the very striking facts adduced by Professor Lister in his various well-known publications on the antiseptic method of treatment. It appears to me impossible to rise from the perusal of those publications without a strong conviction that the lamentable mortality which so frequently dogs the footsteps of the most skilful operator, and those deadly consequences of wounds and injuries which seem to haunt the very walls of great hospitals, and are, even now, destroying more men than die of bullet or bayonet, are due to the importation of minute organisms into wounds, and their increase and multiplication; and that the surgeon who saves most lives will be he who best works out the practical consequences of the hypothesis of Redi.