Hemorrhage and infarction of the spleen are not very common, there being eleven of the former and ten of the latter and all occurring with the same indication or history of infectious disease; in one case, an opossum (_Didelphys virginiana_) an injury probably caused a massive hemorrhage shaped like an infarct. It is, however, curious that of the twenty-one cases only five occurred in birds, of which only one hemorrhage was in the shape to which the term infarction is best applied. There have been, as one might expect, a few cases of infected infarction, with abscess. It is perhaps worth noting that no case of hemorrhagic cyst or inspissated coagulum has been seen. Only one case of rupture is recorded secondary to acute splenitis during an acute septicemia. INFLAMMATIONS. It has been the practice at this laboratory to classify splenitis in three ways, (1) acute diffuse splenitis—general congestion with perhaps small hemorrhages, swelling but retention of general architecture and with no undue prominence of the follicles; (2) follicular hyperplasia— where this is the prominent gross and minute finding, the pulp being less pronouncedly involved; (3) acute splenic tumor—where the organ is greatly enlarged but with loss of the usual markings. Perhaps this separation is not warranted upon a strict etiological basis, and yet as we shall see it holds true fairly well in the toxic and infectious lesions. Moreover, from the following list it is evident how the various orders call upon the splenic tissue in disease.