ACUTE DEEP-SEATED GLOSSITIS. This disease has also been termed parenchymatous and interstitial glossitis, because all the deep-seated tissues, including the muscles and connective tissue layers are involved in the inflammation. =Causes.= The disease may be due to a neglected attack of superficial glossitis, to some grave microbic infection, or to excoriation and ulceration of the mucous membrane. Very often it is of traumatic origin, and is due to violent traction on the tongue by herdsmen or others when administering draughts of their own composition. This traction causes rupture of the muscle and slight interstitial hæmorrhage. =The symptoms= develop somewhat rapidly. Whilst at first the animal shows difficulty in grasping food, it is soon totally incapable of doing so. The tongue loses its mobility, is no longer protruded from the mouth, and swallowing becomes so painful that salivation sets in. On direct examination the tongue is found swollen, thickened, immobile, painful, and occupying the whole of the oral cavity, sometimes projecting beyond the region of the incisors, and preventing the mouth being closed. Inflammation may become so intense that the point of the tongue hangs out of the mouth. It becomes blackish, bleeding, swollen, and excoriated by contact with foreign bodies or simply with the row of incisor teeth. The saliva becomes fœtid, blood-stained and purulent, and contains large quantities of broken down epithelial cells. It is not uncommon to note more or less extensive necrosis. =Diagnosis.= The diagnosis of this form of glossitis presents no difficulty, for if under certain conditions it may resemble, for example, the glossitis of actinomycosis, it differs essentially from that disease by its rapidity of development, by its complications, and also by the absence of the specific ray fungus. =Prognosis.= The prognosis is grave, not only on account of the possible complications, but also because the animals are unable to feed and therefore lose flesh with very great rapidity. =Treatment.= The first steps in treatment are in the nature of local disinfection, in order to prevent general infection. The mouth therefore should be washed out five or six times per day with boiled water, followed by antiseptic injections until improvement commences. Solutions of boric acid or borax (3 per cent.), chlorate of potassium (2 to 3 per cent.), or salicylic acid (3 to 4 per cent.), are useful, but the free employment of 1, 2, or 3 per cent. solutions of chloral is even preferable. With the idea of protecting the organ from external injury, Lafosse formerly suggested the use of a suspensory bandage for the tongue, fixed to the base of the horns by small bandages. Guittard recommends scarification of the free part, and the application of a support perforated at the bottom to allow the blood, saliva, pus, etc., to escape. In spite of careful attention the disease may last from two to three weeks.