With each movement forward, muscular tremors affect the limbs; each step is short, jerky, and convulsive; the respirations and pulse are almost immediately greatly quickened, and the lower lip is hung pendulous, and moved almost unconsciously up and down with a flapping noise against the upper. A patchy perspiration breaks out about the body and quarters, and the tail is outstretched and quivering. At the same time the lines of the face become drawn, the commissures of the lips pulled upwards, the eyes staring and haggard, the eyelids puckered, the nostrils extended, and the whole expression indicative of the intense and agonizing pain of the disease. One can perhaps better give one's client some vague idea of the patient's suffering by likening the pain to the throbbing sensation of a festered finger-nail. Tell him that each hoof of the horse is similarly, or, if anything, more delicately, constructed, that in each foot the same process of 'festering' is going on, and that upon them the animal has perforce to stand. As one might expect, the position of greatest ease is the decumbent. Strange to say, though, in many cases of laminitis the animal persists in maintaining a standing posture. Once down, however, one has sometimes the greatest difficulty in persuading him again to rise. The lying position is so long maintained that bedsores begin to make their appearance, and the animal rapidly loses flesh, not only by reason of the fever and the pain, but by giving to rest the time he should normally give to feeding. Difficulty in rising is greatest when all four feet are affected; is _nearly_ as great when the hind-limbs only are in trouble, but is least when the disease exists alone in the two fore-feet. THE COURSE OF THE DISEASE AND ITS PATHOLOGICAL ANATOMY.--As with most inflammations of any severity, so with this we may consider the pathological changes taking place in the foot under three headings: (a) The period of Congestion; (b) the period of Exudation; (c) the period of Suppuration.