The results of an osteoplastic periostitis are frequently met with in the bones of the foot, and are described by veterinary writers under such headings as 'Pedal Exostoses,' 'Ossifying Ostitis,' and 'Pedal Ossification' (see Figs. 152, 153, 154, and 155). In many of these cases the disease is purely chronic, and the original cause nearly always wanting. When the foot has been subjected to laminitis of some weeks' duration, the same condition is also met with, being at the same time associated with rarefactive osteoplastic ostitis, conditions which we shall shortly describe. Cases we have examined have undoubtedly shown this condition of osteoplastic periostitis, the rarefactive and osteoplastic changes in the bone itself, met with in older cases, occurring no doubt as a result of non-expansion of the horny box. So far as we are able to ascertain, there is every reason to believe that in chronic laminitis the accompanying periostitis leads to the formation of bone, and would, if it were possible, lead to increase in the size of the os pedis. If proof were wanted of this, it is only necessary to point out the increased growth at points where resistance is nil--namely, along the upper margin of the bone (see Fig. 118). However, increase in size elsewhere is prevented by the resistance of the hoof, so that, as the bone-forming process progresses, as it inevitably _must_ under the inflammatory changes going on, it is, as it were, compensated for by rarefaction or bone-absorption changes occurring simultaneously with it. 2. OSTITIS. We shall next deal with the inflammatory changes occurring in the bones themselves, and shall consider them under (_a_): Rarefying or Rarefactive Ostitis, (_b_): Osteoplastic Ostitis, and (_c_): Caries and Necrosis. Inflammatory changes occurring in the medulla we may pass without consideration, for in the bones of the foot the medullary cavity is so small, and the changes taking place in it of such minor importance, that we may do this without in any way seriously prejudicing our work. _(a) Rarefying or Rarefactive Ostitis_.--By this term is indicated an inflammation of the bone attended by its absorption, the absorption being due to the action of certain cells, termed _osteoclasts_. This condition may be due to the pressure of tumours, may occur as the result of injury when a piece of bone is stripped of periosteum, or may be the result of an inflammation occurring in the periosteum elsewhere.