If the animal is allowed to linger, other symptoms will nearly always present themselves before death occurs. Whether in slings or not, a careful watch should be kept upon the sound limb. For some time the patient stands upon it incessantly, but sooner or later it happens that a farther visit show us the animal standing with full weight on the diseased foot, and making painful pawing movements with what before was the sound. We immediately jump to the conclusion 'laminitis.' And so it is, but it is a laminitis brought about by pyæmia. This is indicated by the swollen and oedematous nature of the lymphatics of the limb. Plainly enough they indicate the road by which the poison has travelled. It is in this way: Pus and putrefactive organisms have gained entrance to the lymphatics of the original diseased limb. From these they have rapidly gained the blood-stream and set up infection elsewhere. In this particular instance it is demonstrated by the laminitis and lymphangitis of the previously sound limb. With the poison thus circulating in the blood-stream, we often also get spots of infection commenced in one or other of the more vital organs--notably the lungs or the kidneys. The end of our case is then either a gangrenous pneumonia or complications induced by a condition of widespread pyæmia. With the animal in slings there are one or two other symptoms that call for attention. In many cases, especially with animals of a lymphatic and indolent nature, the use made of them is inordinate. The patient rests so continually in them that alarming swellings commence to make their appearance about the rectum, or in the case of a mare about the vulva. The animal must then be let down at regular intervals and again raised when rest is obtained. A more alarming symptom still is when the animal, instead of resting in the slings by his buttocks, casts his weight bodily into the belly-rest and hangs with a heavy head into the head-stall. This indicates complete exhaustion and a wish for death. Matters should therefore be explained to the owner, and his consent obtained for immediate destruction. _Pathology_.--The pathological changes occurring in suppurative arthritis we shall pass over briefly. It is almost sufficient, in fact, to say that the whole of the joint becomes completely disorganized. The synovial membrane becomes so tremendously thickened and injected as to be scarcely recognisable as such, the thickening in the later stages being due to large growths of granulation tissue which entirely alter the appearance of the membrane as we know it normally. In the early stages the contents of the joint are composed of thin pus and synovia. Later, as destruction of the synovial membrane proceeds, the flow of synovia is stopped, while the pus formation goes on until finally nothing but pus and dead tissue products fill the cavity.