must be continued regularly, late and early, not for days, but perhaps for weeks, at the same time that we prevent the action of such causes as would counteract the effects of the bark, such as poor diet, bad air, confinement[91], &c. Administered in this way, the bark may be rendered really useful, not only in the cure of scrophulous ulceration, but perhaps of many other diseases, whilst, in the common way of prescribing it, little or no benefit is derived from it. [91] See what has been said on this subject when treating of the cure of mortification. The muriated barytes has been recommended by Dr. Crawford[92], and has of late been tried in France by M. Pinel[93] and others. It does not appear to have any influence on tumid glands, or scrophulous tumors; but occasionally it is serviceable in scrophulous ulceration. It is, however, a medicine on which very little dependence can be placed, and which fails in a great majority of instances[94]. [92] See the second volume of Medical Communications. [93] Nosographie Philosophique, Vol. II. p. 238. [94] When it is wished to prescribe it, the following is a very good formula: R. Terræ Ponder. Salit. Chryst. gr. x. Aq. Font. Aq. Cassiæ utriusque uncias iii Syrupi Aurent. uncias ii. Half an ounce of this may be given at first, twice or three times a-day, and gradually increased to such quantity as the stomach can bear without sickness. The muriat of lime has been proposed by M. de Fourcroy; it is given more liberally than the muriated barytes, but it is not more efficacious. Iron by itself, or mixed with the fixed or volatile alkalis, has also been frequently employed, but with very little benefit[95]. [95] This metal was one of the principal ingredients in a remedy used by the Marischal de Rougeres, which consisted of filings of iron, sal ammoniac, salt of tartar, &c. Journal de Med. Tom. XL. p. 219. Burnt sponge, millipedes, vitriolated tartar, and many other trifling remedies, which were at one time in repute, are now deservedly neglected. Cicuta has been greatly recommended by Dr. Fothergill and others[96]. It has very little effect on scrophulous tumors, or mild ulcers; but, when administered freely, it is sometimes of service in the irritable fiery ulcer, which was by the older writers called struma maligna. [96] This is highly recommended by M. Martcau. Journ. de Med. Tom. IV. p. 121. Mercury is another remedy, which at one time was much employed in this disease; but few expect any benefit from it now. Gentle, or what has been called alterative courses, are, however, still recommended by many, with a view to satisfy the patient. Various preparations have been used. Some exhibited the corrosive sublimate, others the calomel, whilst the acetite of mercury, mixed with the powder of vipers and earthworm, with the rust of iron, was much employed on the continent[97]. Antimony has frequently been conjoined with this, but without much benefit.