The effects of the ulcerative action admit of greater variations than
those of the inflammatory, and, therefore, more readily show the
presence of specific action. The healthy ulcerative action exhibits
certain appearances which have been already described, and which are
easily known. The simple deviations which have been treated of, in
considering the different genera of ulcers, are also discoverable by
the effects, or peculiar symptoms. The specific deviations dependent
upon the presence of previous specific inflammation, or the application
of a morbid agent, after simple ulceration has been induced, may
also, in many cases, be detected and ascertained, by the variations
which take place in the aspect of the sore, the appearance of the
granulations, discharge, &c.; but these variations and appearances
consist so much in peculiar hues and qualities of the granulations,
which we have no words to convey an idea of, that it is impossible
to give an accurate description of a specific sore, but must see it
in order to obtain an idea of it. We may indeed say, that a sore is
ragged, has a fiery look, is surrounded with an erysipelatous margin,
and discharges a thin fœtid matter, but still we shall not convey the
idea of the specific appearance of the ulcer.
It is this specific appearance alone which characterises a specific
ulcer; and this, in each peculiar ulcer, is different; and a knowledge
of it can only be obtained by an attentive examination of many sores.
On this account, it is extremely difficult, in many instances, to
distinguish a specific ulcer, because the discrimination depends
altogether upon the recollection of the practitioner, and the
improvement which he has made of his former observations. It is indeed,
it may be thought, an easy matter to distinguish a simple ulcer by
negative characters, or the want of the peculiar aspect; but, as this
aspect is very arbitrary, and as the appearance of simple ulcers is,
as has been already described, very various, it is difficult to say,
without much judgment, whether the sore be simple or specific; for
the appearance of the one and of the other run imperceptibly into each
other. Even if it be ascertained to be specific, it is difficult often
to distinguish betwixt particular specific diseases, in so much, that
many are forced to take mercury for the cure of syphilis, who never had
that disease.
Besides the appearance of the sores, specific action likewise produces
a perceptible effect upon the scab which covers them, or the cicatrix
which is formed. Thus, scrophula is marked by a particular appearance
of the cicatrix, or of the scab. The venereal ulcer has likewise a
particular scab, and many cutaneous ulcers are best distinguished by
the scab. Other actions produce no considerable ulceration, but only
successive desquamation of the cuticle.
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