Therefore when a heart has serious lesions, whether of the myocardium or of the valves, with compensation only sufficient, the action of caffein in any form is contraindicated. The fact that it raises the blood pressure, thus increasing the force against which the heart must act, and that it irritates the heart muscle to more sturdy or irregular contraction, indicates that a patient with a heart lesion or with a nervously irritable heart should never drink tea and coffee or take caffein in any beverage. Many patients cannot sleep for many hours after they have taken coffee or tea, as the cerebral stimulation of caffein is projected for hours after its ingestion. Caffein does not absorb so quickly and therefore does not act so quickly when taken in the form of tea and coffee as it does when taken as the drug or as a beverage which contains the alkaloid. Persons who are nervously irritable, excited and overstimulated cerebrally, with or without high blood pressure, should not take this cerebral and nervous excitant. This is true in early childhood and in youth, and continues true as age advances, in most persons. It is a crime to present caffein as a soda fountain beverage to children and young persons when the excitement of the age is such as already to overstimulate all nervous systems and all hearts. A considerable majority of persons over 40 learn that they cannot drink tea or coffee with their evening meal without finding it difficult to sleep. Such patients, of course, should omit this stimulant. Some patients have already recognized this fact and its cause; others must be told. The majority of adults are probably no worse and may be distinctly benefited by the morning cup of coffee and the noon coffee or tea, provided the amount taken is not large. It seems to be a fact that the drinking of coffee is on the increase, especially as to frequency. Certainly the five o'clock tea, with women, is on the increase, and we must deal with one more cerebral and nervous excitant in our consideration of what we shall do to slow this rapid age. TOBACCO