1. Merry, disposed to sing. Deep sleep, longer than usual, for the first three days. Drowsy all day, with frequent yawning, but no desire to lie down. Insignificant or unpleasant dreams, scarcely recollected on waking. 5. Sleeps longer, the first day. Headache, on waking. Sleepy with yawning, after breakfast, the first day. Drowsy after dinner, but no sleep, second day. Shuddering all over, sweat; the hair stands on end, second day, 9 in the morning. 10. Heaviness of the head on waking, eight hours after taking the drug. Weight at the vertex, which seems to press on the brain, with heaviness of the eyelids and difficulty of opening them, without sleep. Deep-seated and dull pain in the upper part of the brain, worse when touched, talking or sitting; less when walking or moving about, first day. Same symptom on the second day, but less. Sense of fullness in the head, second day. 15. Sense of fullness in the head, as if it would split, especially after twelve o’clock, on the third day. Sensation as if hot water were thrown on the hairy scalp, penetrating to the brain, second day. The headache disappears on the third day, it becomes lighter and changes. Sight feebler and dimmer than usual. Painful heat at the margin of the eyelids, worse when closing the eyes. 20. Dim sight after dinner, second day. Fetid breath. Sensation in the throat as if one had swallowed some astringent substance. Sensation in the mouth and throat as if one had eaten some acrid and resinous fruit, second day, in the morning. Dull pain in the bowels and hypogastrium, second day. 25. Constipation for three days. Copious urination, in the morning. Light-colored, watery urine, without smell or sediment, third day. Violent lancinations cinder the right breast, at each inspiration. Slight pain at the sternum, when stooping. 30. The voice becomes hoarse from much coughing. Weariness and numbness of the left arm, with pain in the humero-cubital articulation, first day. Numbness of the tips of the fingers, especially the ring-finger. Sensation at the middle of the right thigh as if bitten by an ant; itching and heat after scratching. Cramp in the calves during the night, second day. Second prover: _Mlle. Norma_, 21 years old, sanguine temperament, good constitution, pale face, melancholy disposition, chestnut-colored hair.