A short time afterward the doctor writes: “The chloral eater died some few days ago, in Los Angelos. Was found dead in the water closet of his hotel. The despatch says, ‘supposed cause apoplexy.’ I think it was more likely cardiac asthenia.” Dr. R. F. Lewis, of Lumberton, N. C., writes me: “A prominent physician of this place who was intemperate in the use of spirits, morphine, etc., began the use of chloral instead, and for weeks or months was more or less under its influence. He died suddenly after using it in increased quantities the day and night before. No autopsy.” Dr. A. R. Kilpatrick, of Navasota, Texas, sends me the following curious note:— “About four or five years ago there was a doctor living at Port Hudson, West Feliciana Parish, La., named (I think) Harris, who wrote several papers for the _Med. and Surg. Reporter_, of Philadelphia. He wrote one or two papers especially on the use of chloral and on the chloral habit, and very impressively warned people about its use and abuse, and in less than a year after the publication of those pieces I saw his death announced, and that he had been a habitual consumer of chloral, and that it killed him.” Here is another case of death from an overdose, in an habituè, contributed by Dr. S. Henry Dessau, of this city:— “The only case where I have known death to be in any way connected with the administration of chloral, was in a case of dipsomania in a hysterical female. I prescribed a combination of fifteen grains of chloral with thirty grains of bromide of potassium, to be repeated every two hours, until sleep was procured; the effect was obtained after three or four doses. About eight doses were given in the mixture. I ceased attending the case, and about a year after learned through the press that the patient had died from an overdose of chloral. On inquiring from the druggist who had prepared the prescription, I learned that the patient continued to use the medicine steadily after my visits ceased, and that for twenty-four hours before death she had used two bottles of the mixture, or in other words four ounces of chloral with one ounce of bromide of potassium.” Two cases of chloral habituation in men past middle age are reported by Dr. C. A. Bryce of Richmond, Va., where death occurred from _symptoms resembling apoplexy_. THE HASHISCH HABIT. CHAPTER XII. HASHISCH INTOXICATION. A common practice in some of the far Eastern countries—hashisch taking—is comparatively rare among the people of civilized nations. Here, as there, the practice is not one of steady, daily intoxication with this drug, but it, more like alcohol, is resorted to at certain times, when the system seems especially to crave it, or the temptation is offered. In this it differs materially from the practice of opium or morphia taking. In point of continual craving, we might, I think, arrange these drugs in the following order: Morphine or opium, chloral, hashisch, alcohol.