October 20. Patient has slept altogether for five hours during the night, with many interruptions. During the intervals, besides being restless, there was prostration, craving for morphia, nausea, and frequent vomiting, and pains in the stomach. In the morning sneezing and yawning. During the daytime the condition was comparatively good. _Left pupil wider than the right, towards the evening the contrary taking place._ At 8.30 P.M. patient had a bath at 31° R. (87.8° F.) of half an hour’s duration, with cold douche. October 21. Restless during the whole of the night, craving for morphia and increased reflex action. During the daytime the condition of the patient is satisfactory, excepting some yawning, sneezing, and slight prostration. October 22. No sleep during the night, paroxysms of sneezing and yawning. October 23. Patient slept for three hours with interruptions. Towards the morning severe sneezing. Appetite good. She had a bath, with cold douche, morning and night. October 24. Patient was very restless in the night, moved about in the bed, and in the morning was much exasperated on account of the bad night. At 9 P.M. 40 grains of chloral were given in gruel, but were immediately brought up again. October 26. Patient slept for two hours with interruptions. During the remainder of the night she felt oppressed and had palpitations of the heart. Sneezing the same as yesterday. October 28. Very restless during the night. Patient had only about one hour’s sleep towards the morning, and then felt pains in the lower part of the abdomen. October 29. Has had hardly any sleep during the night. Mental condition nevertheless good; appetite the same. October 31. During the past nights she slept, on the average, for three hours. Meals are taken regularly. Thirty grains of chloral were given in capsules. Patient in the daytime complains of labor-like pains in the lower abdominal region. November 1. Patient slept for several hours after having taken 30 grains of chloral. The pains in the hypogastric region are still apparent now and then; some reddish watery spots show on the linen. November 2. The pains have increased in the morning; the whole abdominal region is sensitive to the touch. Poultices were applied. _In the middle of the day the menstrual discharge shows itself._ November 3. The pains have abated. Patient has slept for four hours. November 4. Menstrual discharge still continues. While it is said formerly to have lasted only for a few hours, it has now lasted for forty-eight hours. Toward midday the patient left her bed and remained on the couch for several hours. November 5. Slept from 11 P.M. till 2.30 A.M. Patient felt oppressed in the night; there was difficult breathing, and she could not remain in bed. Patient leaves the Institution on November 15th, all bodily functions having become regular. She has up to the present time had no relapse.