This severity on the part of the home government has naturally given rise to several attempts to cast off the Spanish yoke. The first occurred in 1823, when Simon Bolivar offered to aid the disaffected party by throwing an invading force into the island. Another was made in 1826, and a third in 1828. In 1848 a conspiracy was formed at Cienfuegos and Trinidad to establish Cuban independence, under the leadership of General Narciso Lopez; but finding that his plans were premature, he escaped to this country, and here arranged a descent upon the island, which he led in person: this was in 1850. General Lopez, however, was not seconded by the timid natives, though they had freely pledged themselves to do so, and his expedition, after winning one decisive battle and several important skirmishes, was at last overpowered and its leader promptly executed. General Lopez was an adopted citizen of Cuba, and was married to one of her daughters. He was executed at the age of fifty-two. The Lopez expedition would seem to have been the most serious and best organized attempt at revolution in Cuba by invasion, though there have been formidable attempts since. From 1868 to 1876 Cuba may be said to have been in a state of chronic civil war. This outbreak was led by Carlos Manuel de Cespedes, an able lawyer and wealthy planter of Bayamo, in the eastern department of the island. He raised the standard of independence on his estate, Demajagua, supported at the outset by less than fifty men. This was in October, 1868, and by the middle of November he had an organized army of twelve thousand men; poorly armed, it must be admitted, but united in purpose and of determined will. That portion of the island contiguous to Santiago, and between that city and Cienfuegos, was for a long period almost entirely in possession of the patriot forces. Here many sanguinary battles were fought with varying fortune, at terrible sacrifice of life, especially on the part of the government troops, over one hundred thousand of whom, first and last, are known to have perished in that district. Spain actually sent one hundred and forty-five thousand enlisted men to Cuba during the eight years of active warfare. Of this number those who finally returned to the European peninsula were but a few hundreds! It was publicly stated in the Cortes of Madrid that not enough of that immense force ever returned to fill a single regiment! The climate was far more fatal to these soldiers than were patriot bullets. The warfare was conducted by the native Cubans mostly on the guerrilla plan, and was ten times more destructive to the imported soldiers than to themselves. Discipline counted for little or nothing in contending with men who fought single-handed and from ambush, decimating the ranks of an invading column, who in turn could only fire at random.