comparative rest; consequently, coagulation occurs in this situation.
The internal coagulum, however, is small, and not sufficient to occupy
completely the cavity of the vessel; it is of a conical form, its apex
being towards the heart, and opposite to the first collateral branch,
and its base resting on the external coagulum, and there adhering to
the internal surface of the artery. But, whilst this latter process
is advancing, the capillary vessels supplying the cut margins of
the artery have begun to act; they throw out coagulating lymph, and
continue to do so until their secretion has completely filled the
vessel immediately opposite to its divided margins; thus a third and
more effectual coagulum is formed,—one of plastic matter, situated
between the external and internal coagula of blood, and in general
closely adherent to them. Lymph is also effused externally to the
artery and its sheath, forming a dense stratum, which separates the
extremity of the vessel from the external wound; it becomes organised,
forms granulations, and thus the parts are consolidated, and the wound
cicatrised. When the artery is permanently obstructed by the adhesion
of its cut margins, the external coagulum can be dispensed with, and
is gradually absorbed. Afterwards all the newly formed parts are
condensed, and diminish in size; the artery contracts, its internal
surface finally embraces the coagulated blood which lay loose in its
canal; its coats appear to be thickened, and it is firm and hard.
Ultimately, in consequence of the continuance of absorption, it becomes
much more attenuated, so as scarcely to differ from the surrounding
cellular tissue. Similar changes occur in the lower extremity of the
divided artery; in general it retracts farther, its orifice is more
contracted, and, the flow of blood being much less profuse than in
the superior, the natural means for its temporary closure are sooner
accomplished. When an artery has been divided close to the origin of
a collateral branch, no bloody coagulum can form internally, for the
blood in that situation is necessarily in a state of constant motion.
Public-domain text, read in full here on John Shaqi.
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