In January 1803 was founded the Royal Jennerian Institution, under royal patronage, and with Jenner as president, to propagate vaccination in London and elsewhere. This continued its operations for some years with distinguished success; but Dr. Walker, who had been appointed resident inoculator, soon began to deviate from Jenner’s instructions, and to adopt methods calculated in Jenner’s view to bring the practice into disrepute. Consequently the dismissal of Walker was called for, but was negatived in one division, to which Walker had brought in as voters twenty persons who only paid their subscription on the day of voting. By such absurd possibilities are the steps of benefactors to their race frequently beset. The resignation of Dr. Walker took place soon afterwards, but the Jennerian Institution did not fully recover from the effects of the dissension, and on the establishment of the National Vaccine Institution in 1808 it became practically extinct. Will it be credited that, after the decisive parliamentary vote, for more than two years the Treasury delayed to pay the money, on one pretence and another; and when at last it was paid, nearly £1000 was deducted on account of fees. Akin to this, though the amount was trifling, was a demand made upon Jenner for five pounds admission fees, when the corporation of Dublin conferred upon him the freedom of that city. Among the multitude of testimonies of appreciation which Jenner received, not the least interesting is one which proceeded from the chiefs of the “Five Nations” of Canadian Indians, the Mohawks, the Onondagas, the Senecas, the Oneidas, and the Coyongas. Their address to him ran as follows: “Brother! our Father has delivered to us the book you sent to instruct us how to use the discovery which the Great Spirit made to you, whereby the smallpox, that fatal enemy of our tribes, may be driven from the earth. We have deposited your book in the hands of the man of skill whom our Great Father employs to attend us when sick or wounded. We shall not fail to teach our children to speak the name of Jenner; and to thank the Great Spirit for bestowing upon him so much wisdom and so much benevolence. We send with this a belt and string of wampum, in token of our acceptance of your precious gift; and we beseech the Great Spirit to take care of you in this world, and in the land of spirits.”