In 1813 the degree of M.D. was voted to Jenner by the University of Oxford. It was expected that the London College of Physicians would have followed suit by admitting him to membership, but they exacted a full examination, which Jenner at his age, and with his reputation, could not be expected to submit to. In the summer of 1814 Jenner visited London for the last time, being presented to the Czar, and having numerous interviews with his sister, the Grand Duchess of Oldenburg. On the 13th September, 1815, Mrs. Jenner died, a calamity which most deeply afflicted Dr. Jenner, and seemed to mark his retirement from active public life. It is much to be regretted that he did not live to complete and publish his own final account, and matured convictions, as to the suitable conditions of vaccination, and the modifications and imperfections to which it was liable. This engaged much of his attention in his later years, but his inquiries were interrupted by illness and by family affliction. His later years were made painful by extreme nervous sensitiveness, and he had several attacks which foreboded death by apoplexy, which ultimately occurred on 26th January, 1823. He was buried at Berkeley, by the side of his wife, on 3d February. Jenner’s nature, says his biographer, was mild, unobtrusive, unambitious; the singleness of his heart and his genuine modesty graced and adorned his splendid reputation. Had those who opposed him known how little of selfishness, vanity, or pride entered into his composition! He made no answer to aspersions. “All the friends who watched him longest, and have seen most of his mind and of his conduct, with one voice declare that there was a something about him which they never witnessed in any other man. The first things that a stranger would remark were the gentleness, the simplicity, the artlessness of his manner. There was a total absence of all ostentation or display; so much so, that in the ordinary intercourse of society he appeared as a person who had no claims to notice. He was perfectly unreserved, and free from all guile. He carried his heart and his mind so openly, so undisguisedly, that all might read them. You could not converse with him, you could not enter his house nor his study, without seeing what sort of man dwelt there.”