Brodie may now be regarded as firmly established in public favour. His income in 1819 exceeded that of the preceding year by £1000. He enjoyed the intimate acquaintance of Lord and Lady Holland, and the sunshine of their friendship had its strong influence on practice. In 1819 Brodie removed to Savile Row, and in the same year was appointed to succeed Lawrence as Professor of Comparative Anatomy and Physiology at the College of Surgeons. In this capacity he lectured for four years, delivering new and original matter each time. They constituted a frightful addition to his labours, and he only completed them by taking many hours from needed sleep. He records, however, that few things contributed more to his improvement than the composition of his lectures, and the habit of recording his knowledge and thoughts. It enabled him to detect his own deficiencies, and to avoid hasty conclusions, and taught him to be less conceited of his own opinions. An important branch of modern surgery may be said to have had its rise in an operation first performed by Brodie. Nowadays subcutaneous operations, in which the slightest possible opening is made in the skin, and frequently considerable incisions or other interferences are made beneath it, are very common, and the procedure is of the greatest importance in orthopædic surgery and the relief of muscular and tendinous contractions of various kinds. Brodie first performed a subcutaneous operation for the relief of varicose veins of the legs in 1814, and several similar cases were published by him in the seventh volume of the “Medico-Chirurgical Transactions.” If no other operative improvement of great moment is associated with Brodie’s name, it is not that he has not left his mark on that department of practice, but rather that he has been the introducer of innumerable minor improvements. In particular, he was notable in devising improvements in surgical instruments and apparatus.