In 1780-2 Gregory published his “Conspectus Medicinæ Theoreticæ,” written in excellent Latin; it speedily became widely known, and was extensively read not only in Britain but also on the Continent. It has gone through numerous editions. Its more important and valuable portions were those dealing with therapeutics. In 1790 he was appointed Cullen’s successor in the chair of the Practice of Medicine, and from that time continued to lecture to large classes down to his death in 1821 (April 2). Thus he held an almost autocratic position for the long period of over thirty years; and it is much to be regretted that his great talents in repartee, quick memory for telling quotations, and fondness for a joke, led him to take an active part in the medical controversies which have embittered so many careers in Edinburgh. The long list of controversial books and pamphlets by Dr. Gregory, given by Mr. John Bell in his “Letters on Professional Controversy and Manners,” 1810, could be considerably extended, and it affords a melancholy picture of misplaced energy. One of these extended to 700 pages quarto, and its tone may be judged from the following extracts from the “Memorial to the Managers of the Royal Infirmary.” “Let us suppose that in consequence of this memorial, every individual member of the College of Surgeons shall, to his own share, make forty times more noise than Orlando Furioso did at full moon when he was maddest, and shall continue in that unparalleled state of uproar for twenty years without ceasing. I can see no great harm in all that noise; and no harm at all to any but those who make it.... Ninety-nine parts in the hundred of all that noise would of course be bestowed on me; whom it would not deprive of one hour of my natural sleep, and to whom it would afford infinite amusement and gratification while I am awake.”