The year 1841 was marked by the first public steps taken to establish the Hospital for Consumption and Diseases of the Chest, which originated with Mr. (afterwards Sir) Philip Rose. A clerk in his firm suffering consumption found no hospital willing to admit him, on the plea of the lingering and incurable nature of the disease. This started the idea of a special hospital, which Dr. Williams cordially supported, and to which he became consulting physician. The history and great success of the Brompton Hospital cannot be followed here; in 1882 it had 331 beds. The great Virchow, when he visited it in 1881, said, “Here _everything_ is done for the sick.” In 1843 Dr. Williams published the “Principles of Medicine,” a work in which physiology and pathology were largely employed to form a basis for scientific medicine. It was received with high approval, and became a standard work in America. New editions appeared in 1848 and in 1856. Sir James Paget and Sir James Simpson among others have given it the stamp of their marked approbation. The _Lancet_ gave it almost unqualified praise. In 1846 the Pathological Society of London was established, and Dr. Williams was chosen its first president. Its objects were the exhibition, description, and classification of morbid specimens, and the promotion of pathological research by systematic observation and experiments. In his opening address, Dr. Williams answered the sceptical question, “What is the use of opening bodies? We never find what we expected:” by describing a _post mortem_ examination of a remarkable case of pulmonary disease. The examination had been concluded before Dr. Williams arrived, and he was told that there was enlargement of the heart, which the physician in charge expected, and was satisfied. Dr. Williams insisted on careful inspection of the lungs, which disclosed extensive consolidation, and in addition an unexpected general dilatation of the bronchial tubes. This was the case in which he first discovered the connection between that change and pleuro-pneumonia. The very appropriate motto of the Society, “Nec silet mors,” was suggested by Dr. Williams.