We cannot go into the controversy as to which American has the greatest merit in the introduction of sulphuric ether as an anæsthetic. Suffice it to mention that Charles Jackson, a chemist of Boston, who had been present at Wells’ demonstration in 1840, first experimented on himself by inhaling pure sulphuric ether, and having produced insensibility, communicated his discovery to W. T. G. Morton, a dentist who had been present at Wells’ demonstration, and prevailed on him to employ it. Morton afterwards alleged that this step was taken independently on his part. On September 30, 1846, Morton administered ether to Eben Frost for tooth-drawing with complete success, and in October following it was used in an important operation by Dr. J. C. Warren at the Massachusetts General Hospital. The news arrived in England before the end of 1846, and on December 19th, James Robinson, a dentist of Gower Street, London, was the first to operate under ether in this country for the removal of a tooth. On December 21 Robert Liston employed it most successfully at University College Hospital in an amputation of the thigh and in the removal of a great toe-nail, one of the most exquisitely painful operations. Its general adoption followed in the first few months of 1847. Dr. Simpson, as early as January 9, 1847, after previously inhaling it himself, used it in order to relieve pain in childbirth, and found that its anæsthetic effects produced no stoppage or perceptible alteration in the muscular contractions of the womb. This and other cases of his were quickly published, and justify his claim to having introduced ether in its application to midwifery practice.