such as that of the deltoid or the gluteal region. The indications for
the use of ergot in obstetrics are highly complex and demand detailed
treatment. It can only be said here that the drug should only in the
rarest possible cases be given whilst the child is still _in utero_.
This rule is necessitated by the sphacelinic acid, which causes an
unnatural state of the organ. When it is possible to obtain pure
cornutine, which is unfortunately very expensive, the precautions
necessary in other cases may be abrogated.
_Chronic poisoning_, or _ergotism_, used frequently to occur amongst the
poor fed on rye infected with the _Claviceps_. As it is practically
impossible to reproduce the symptoms of ergotism nowadays, whether
experimentally in the lower animals, or when the drug is being
administered to a human being for some therapeutic purpose, it is
believed that the symptoms of ergotism were rendered possible only by
the semi-starvation which must have ensued from the use of such
rye-bread; for the grain disappears as the fungus develops. There were
two types of ergotism. In the gangrenous form various parts of the body
underwent gangrene as a consequence of the arrest of blood-supply
produced by the action of sphacelinic acid on the arteries. In the
spasmodic form the symptoms were of a nervous character. The initial
indications of the disease were cutaneous itching, tingling and
formication, which gave place to actual loss of cutaneous sensation,
first observed in the extremities. Amblyopia and some loss of hearing
also occurred, as well as mental failure. With weakness of the voluntary
muscles went intermittent spasms which weakened the patient and
ultimately led to death by implication of the respiratory muscles. The
last-known "epidemic" of ergotism occurred in Lorraine and Burgundy in
the year 1816.
ERIC XIV. (1533-1577), king of Sweden, was the only son of Gustavus Vasa
and Catherine of Saxe-Lauenburg. The news of his father's death reached
Eric as he was on the point of embarking for England to press in person
his suit for the hand of Queen Elizabeth. He hastened back to Stockholm,
after burying his father, summoned a _Riksdag_, which met at Arboga on
the 15th of April 1561, and adopted the royal propositions known as the
Arboga articles, considerably curtailing the authority of the royal
dukes, John and Charles, in their respective provinces. Two months
later Eric was crowned at Upsala, on which occasion he first introduced
the titles of baron and count into Sweden, by way of attaching to the
crown the higher nobility, these new counts and barons receiving
lucrative fiefs adequate to the maintenance of their new dignities.
Public-domain text, read in full here on John Shaqi.
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