The history of the house now becomes involved and of little interest until we come to Nicholas III. (1384-1441), who exercised sway over Ferrara, Modena, Parma and Reggio, waged many wars, was made general of the army of the Church, and in his later years governor of Milan, where he died, not without suspicion of poison. To him succeeded Lionello (1407-1450), a wise and virtuous ruler and a patron of literature and art; then Borso (1413-1471), his brother, who was created duke of Modena and Reggio by the emperor Frederick III., and duke of Ferrara by the pope. In spite of the wars by which all Italy was torn, Ferrara enjoyed a period of peace and prosperity under Borso; he patronized literature, established a printing-press at Ferrara, surrounded himself with learned men, and his court was of unparalleled splendour. He also protected industry and commerce, and ruled with great wisdom. His brother Ercole I. (1431-1505), who succeeded him in 1471, was less fortunate, and had to engage in a war with Venice, owing to a dispute about the salt monopoly, with the result that by the peace of 1484 he was forced to cede the district of Polesine to the republic. But the last years of his life were peaceful and prosperous, so that afterwards men looked back to the days of Ercole I. as to a golden age; his capital was noted both for its luxury and as the resort of men eminent in literature and art. Boiardo the poet was his minister, and Ariosto obtained his patronage. Ercole's daughter Beatrice d'Este (1475-1497), duchess of Milan, one of the most beautiful and accomplished princesses of the Italian Renaissance, was bethrothed at the age of five to Lodovico Sforza (known as _il Moro_), duke of Bari, regent and afterwards duke of Milan, and was married to him in January 1491. She had been carefully educated, and availed herself of her position as mistress of one of the most splendid courts of Italy to surround herself with learned men, poets and artists, such as Niccolo da Correggio, Bernardo Castiglione, Bramante, Leonardo da Vinci and many others. In 1492 she visited Venice as ambassador for her husband in his political schemes, which consisted chiefly in a desire to be recognized as duke of Milan. On the death of Gian Galeazzo Sforza, Lodovico's usurpation was legalized, and after the battle of Fornovo (1495) both he and his wife took part in the peace congress of Vercelli between Charles VIII. of France and the Italian princes, at which Beatrice showed great political ability. But her brilliant career was cut short by death through childbirth, on the 3rd of January 1497. She belongs to the best class of Renaissance women, and was one of the culture influences of the age; to her patronage and good taste are due to a great extent the splendour of the Castello of Milan, of the Certosa of Pavia and of many other famous buildings in Lombardy.