The first patient was treated by Pasteur's system in July 1885. He was successively inoculated with emulsions made from cords that had been kept fourteen and ten days, then eleven and eight days, then eight, seven, six days, and so on. Two forms of treatment are now used--(1) the "simple," in which the course from weak to strong virus is extended over nine days; (2) the "intensive," in which the maximum is reached in seven days. The latter is used in cases of very bad bites and those of some standing, in which it is desirable to lose no time. Two days are compressed into one at the commencement by making injections morning and evening instead of once a day, so that the fifth-day cord is reached in four days instead of six, as in the "simple" treatment. When the maximum--the third-day cord--is reached the injections are continued with fifth-, fourth-, and third-day cords. The whole course is fifteen days in the simple treatment and twenty-one in the intensive. The doses injected range from 1 to 3 cubic centimetres. Injections are made alternately into the right and left flanks. The following table shows the number treated from 1886 to 1905, with the mortality. +------+--------+-------+---------+ | Year.|Patients|Deaths.|Mortality| | |Treated.| |per cent.| +------+--------+-------+---------+ | 1886 | 2671 | 25 | .94 | | 1887 | 1770 | 14 | .79 | | 1888 | 1622 | 9 | .55 | | 1889 | 1830 | 7 | .38 | | 1890 | 1540 | 5 | .32 | | 1891 | 1559 | 4 | .25 | | 1892 | 1790 | 4 | .22 | | 1893 | 1648 | 6 | .36 | | 1894 | 1387 | 7 | .50 | | 1895 | 1520 | 5 | .33 | | 1896 | 1308 | 4 | .30 | | 1897 | 1521 | 6 | .39 | | 1898 | 1465 | 3 | .20 | | 1899 | 1614 | 4 | .25 | | 1900 | 1419 | 10 | .70 | | 1901 | 1318 | 5 | .37 | | 1902 | 1105 | 2 | .18 | | 1903 | 630 | 4 | .65 | | 1904 | 757 | 5 | .66 | | 1905 | 727 | 4 | .54 | +------+--------+-------+---------+