intolerant missive; the Franciscan John of Capistrano moved the masses to activity by his eloquent denunciations; even Casimir IV. revoked the privileges of the Jews in Poland, when the Turkish capture of Constantinople (1453) offered a new asylum for the hunted Jews of Europe. But in Europe itself the catastrophe was not arrested. The Inquisition in Spain led to the expulsion of the Jews (1492), and this event involved not only the latter but the whole of the Jewish people. "The Jews everywhere felt as if the temple had again been destroyed" (Graetz). Nevertheless, the result was not all evil. If fugitives are for the next half-century to be met with in all parts of Europe, yet, especially in the Levant, there grew up thriving Jewish communities often founded by Spanish refugees. Such incidents as the rise of Joseph Nasi (q.v.) to high position under the Turkish government as duke of Naxos mark the coming change. The reformation as such had no favourable influence on Jewish fortunes in Christian Europe, though the championship of the cause of toleration by Reuchlin had considerable value. But the age of the ghetto (q.v.) had set in too firmly for immediate amelioration to be possible. It is to Holland and to the 17th century that we must turn for the first real steps towards Jewish emancipation. 47. _Period of Emancipation._--The ghetto, which had prevailed more or less rigorously for a long period, was not formally prescribed by the papacy until the beginning of the 16th century. The same century was not ended before the prospect of liberty dawned on the Jews. Holland from the moment that it joined the union of Utrecht (1579) deliberately set its face against religious persecution (_Jewish Encyclopedia_, i. 537). Maranos, fleeing to the Netherlands, were welcomed; the immigrants were wealthy, enterprising and cultured. Many Jews, who had been compelled to conceal their faith, now came into the open. By the middle of the 17th century the Jews of Holland had become of such importance that Charles II. of England (then in exile) entered into negotiations with the Amsterdam Jews (1656). In that same year the Amsterdam community was faced by a serious problem in connexion with Spinoza. They brought themselves into notoriety by excommunicating the philosopher--an act of weak self-defence on the part of men who had themselves but recently been admitted to the country, and were timorous of the suspicion that they shared Spinoza's then execrated views. It is more than a mere coincidence that this step was taken during the absence in England of one of the ablest and most notable of the Amsterdam rabbis. At the time, Menasseh ben Israel (q.v.) was in London, on a mission to Cromwell. The Jews had been expelled from England by Edward I., after a sojourn in the country of rather more than two centuries, during which they had been the licensed and oppressed money-lenders of the realm, and had--through