The problem of the succession to the throne was at last settled by the birth of a prince in October (1537). There was now an heir whose claims if he lived would be unassailable. But within a few weeks the queen died; and there was still only the life of one baby to shield the country from anarchy, in case Henry himself should die. With probably genuine reluctance, the King agreed that he would marry again if a suitable wife could be found for him; and the whirligig of intriguing for his union with one or another foreign princess was set in motion; princesses related to Charles, or to Francis, or to one of the Lutheran chiefs. Two years elapsed before the choice was made which, led to Cromwell's downfall. And in the meantime Mary of Guise (or Lorraine) was withdrawn from the lists by her marriage with James V., whose Queen Madeleine had died a few months after the nuptials: while the Duchess of Milan, a youthful niece of the Emperor, was for some time utilised by Charles as a diplomatic asset. The risk of an Anglo-Imperial alliance was employed by him in negotiations with Francis; and when these negotiations were brought to a successful issue the proposed alliance was gradually allowed to drop. [Sidenote: 1538 Diplomatic moves] During 1538 however, this marriage was being dangled before Henry, accompanied by the hope that it might cause a rupture between Charles and the Pope, from whom a dispensation would be necessary--a question which could not now be raised without the kindling of explosive materials. Further the English quarrel with Rome was being embittered by a campaign against spurious relics, miracle-working shrines, and the like, involving a particularly virulent attack on St. Thomas of Canterbury, the type of defiant ecclesiasticism. Moreover, the arrival of a deputation of Lutheran divines in England was ominous of the closer association of the bodies which had revolted from Rome. Reginald Pole, a member of the house which stood high in the Yorkist line of succession [Footnote: See _Front_.], who had been not long before raised to the Cardinalate, had for some time been carrying on from the Continent a violent propaganda against Henry. Pope Paul's Bull of Deposition was again being talked of, though there is some doubt as to whether it was actually published. [Sidenote 1: The Exeter Conspiracy] [Sidenote 2: Cromwell strikes]