════════╤════════╤═════════════════╤═════════════════╤═════════════════ │ NO. OF │ │ │ PNEUMOCOCCUS II │CULTURES│ PNEUMOCOCCUS I │ PNEUMOCOCCUS II │ (Atyp.) ────────┼────────┼────────┬────────┼────────┬────────┼────────┬──────── │ │ NO. │PER CENT│ NO. │PER CENT│ NO. │PER CENT │ │POSITIVE│POSITIVE│POSITIVE│POSITIVE│POSITIVE│POSITIVE ────────┼────────┼────────┼────────┼────────┼────────┼────────┼──────── Bronchus│ 14│ 2│ 14.3│ 1│ 7.1│ 3│ 21.4 Lung │ 19│ 1│ 5.3│ │ │ 5│ 26.3 Blood │ 33│ 2│ 6.1│ 3│ 9.1│ 4│ 12.1 ────────┴────────┴────────┴────────┴────────┴────────┴────────┴──────── ════════╤═════════════════╤═════════════════ │ │ │PNEUMOCOCCUS III │ PNEUMOCOCCUS IV ────────┼────────┬────────┼────────┬──────── │ NO. │PER CENT│ NO. │PER CENT │POSITIVE│POSITIVE│POSITIVE│POSITIVE ────────┼────────┼────────┼────────┼──────── Bronchus│ │ │ 3│ 21.4 Lung │ │ │ 6│ 31.6 Blood │ │ │ 12│ 36.4 ────────┴────────┴────────┴────────┴──────── There is no noteworthy difference in the occurrence of these types of pneumococci among instances of lobar pneumonia, on the one hand, and of combined lobar and bronchopneumonia, on the other. Different types exhibit no noteworthy differences in their ability to penetrate into lungs and blood. =Hemolytic Streptococcus with Lobar Pneumonia.=—There can be no doubt that the concurrent infection with microorganisms other than pneumococcus modifies the progress of lobar pneumonia. With lobar pneumonia alone hemolytic streptococci have entered the bronchi in 30 per cent of instances and have penetrated into the lungs in 20.6 per cent; with associated lobar and bronchopneumonia the same microorganism has entered the bronchi in 34.3 per cent of instances and invaded the lung in 31.6 per cent. Hemolytic streptococci are the only microorganisms other than pneumococci which, in association with lobar pneumonia, have found their way from the lungs to the blood stream; more than one-third of all instances of lobar pneumonia in which hemolytic streptococci find entrance into the bronchi die with streptococcus septicemia. Separation of instances of lobar pneumonia into groups on the basis of the occurrence of red or gray hepatization shows that infection with hemolytic streptococcus is more likely to occur during the early stages of the disease. The average duration of lobar pneumonia with red hepatization has been 3.7 days, with red and gray hepatization, 5.1 days, and with gray hepatization, 7.5 days. Infection with hemolytic streptococcus has occurred in association with red or gray hepatization as shown in Table XXXIII. TABLE XXXIII