Epidemic Respiratory Disease: The pneumonias and other infections of the repiratory tract accompanying influenza and measlesOpie, Eugene L. (Eugene Lindsay)
History
Epidemic Respiratory Disease: The pneumonias and other infections of the repiratory tract accompanying influenza and measles
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AUTOPSY │ BLOOD │ LUNG │ BRONCHUS
─────────────────┼─────────────────┼─────────────────┼─────────────────
283 │Pneum. IV │Staph., B. inf. │B. inf., Pneum.
│ │ │ IV, staph.
291 │0 │0 │B. inf., staph.
398 │0 │ │
419 │0 │Pneum. II, B. │Pneum. II, B.
│ │ inf. │ inf.
421 │S. hem. │Pneum. IV, S. │
│ │ hem. │
422 │0 │Pneum. II atyp., │
│ │ B. inf. │
425 │S. hem. │S. hem., B. inf.,│
│ │ S. alb. │
433 │0 │S. hem., B. inf.,│
│ │ S. aur. │
460 │S. hem. │S. hem., B. inf. │S. hem., B. inf.,
│ │ │ staph.
463 │0 │B. inf., staph. │B. inf., staph.,
│ │ │ Pneum. IV
─────────────────┴─────────────────┴─────────────────┴─────────────────
B. influenzæ has been present in the bronchi in every instance save one
in which cultures have been made, and it is probable that in this
exceptional instance cultures have remained sterile because the media
employed have been defective. The incidence of B. influenzæ in the lung
has been unusually high both with and without organization (66.7 per
cent with no organization; 77.8 per cent with organization).
Streptococci and staphylococci have been found in a considerable
proportion of all instances of peribronchial fibrinous pneumonia, but
there has been no notable preponderance of these microorganisms when
organization has occurred. Organization has been present in instances in
which pneumonia is referable to pneumococcus associated with B.
influenzæ and unaccompanied by either streptococci or staphylococci
(Autopsies 419 and 422). Wadsworth[81] found no organization after
inoculation of the lungs of dogs with pneumococcus or with
staphylococcus alone, but produced organization when he inoculated
animals with both microorganisms.
Injury to bronchi produced in part at least by B. influenzæ exposes the
bronchi and lung tissue to repeated infection with a variety of
microorganisms; absorption of fibrin and regeneration of alveolar
epithelium are prevented, resolution fails to occur and organization of
fibrin follows.
Suppurative Pneumonia With Necrosis and Abscess Formation
Three varieties of suppurative pneumonia have occurred in association
with influenza.
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