Epidemic Respiratory Disease: The pneumonias and other infections of the repiratory tract accompanying influenza and measlesOpie, Eugene L. (Eugene Lindsay)
History
Epidemic Respiratory Disease: The pneumonias and other infections of the repiratory tract accompanying influenza and measles
In over 80 per cent of instances of pulmonary abscess hemolytic
streptococcus has been found in blood, lungs and bronchus and, when
cultures have been made, in the inflamed pleural cavity as well.
Streptococci have been found in immense number in sections from the
necrotic lung tissue and the abscesses which have been formed. It is
evident that hemolytic streptococci have caused suppurative pneumonia
and death, being found in the blood of the heart just as frequently as
in the lungs (83 per cent). The relative unimportance of pneumococci is
indicated by their low incidence in the blood (16.2 per cent) when
compared with that of lobar pneumonia (65.5 per cent) or of
bronchopneumonia (31.4 per cent). B. influenzæ has been found in
three-fourths of these autopsies in the bronchus, but its incidence in
the lungs has been much smaller.
In 3 instances of suppurative pneumonia with abscess formation no
hemolytic streptococci were found; they are as follows:
=Autopsy 380.=—Bronchopneumonia with gray and red lobular
consolidation in right upper and lower lobes; peribronchiolar
nodules of consolidation in left lower lobe; abscess, 1.5 cm.
across, below the pleura of the posterior border of the left lower
lobe near its base; fibrinopurulent pleurisy (300 c.c.) on right
side; serous pleurisy (200 c.c.) on left. Pneumococcus III was found
in cultures from the blood of the heart from the right lung and with
B. influenzæ from the right pleural cavity. No culture was made from
the left lung which contained the abscess. In sections of the
abscess gram-positive streptococci in chains of 4 to 8 cocci were
numerous.
=Autopsy 406.=—Acute lobar pneumonia with red hepatization of
greater part of right lung; patch of consolidation in lower lobe of
left lung containing an abscess cavity 2.5 x 1.5 cm.; localized
seropurulent pleurisy (375 c.c.) on left side. Pneumococcus IV was
obtained from the blood of the heart; a culture from the lung was
contaminated. Tissue from the abscess was not saved for histologic
examination.
=Autopsy 416.=—Suppurative pneumonia with necrosis and abscess
formation in right lower lobe; fibrinous pleurisy on right side.
Pneumococcus IV was obtained from the blood, right lung and right
main bronchus. No streptococci were found in sections from the
abscess in the right lung.
The foregoing observations demonstrate that suppurative pneumonia with
abscess formation following influenza is with few exceptions caused by
S. hemolyticus.
The autopsies (Table XLVI) in which pneumococci have been found in
association with hemolytic streptococci in the blood or lungs indicate
that pneumococci have had a part in the production of fatal pneumonia.
TABLE XLVI
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