Epidemic Respiratory Disease: The pneumonias and other infections of the repiratory tract accompanying influenza and measlesOpie, Eugene L. (Eugene Lindsay)
History
Epidemic Respiratory Disease: The pneumonias and other infections of the repiratory tract accompanying influenza and measles
The pericardial cavity contains 25 c.c. of creamy, yellow, purulent,
fluid; the epicardium is dull, covered in a few places by a small
amount of fibrin and below it are ecchymoses.
The peritoneal cavity contains 100 c.c. of thick, yellow pus; the
peritoneal surfaces are injected and between the liver and diaphragm
is fibrin.
Bacteriologic examination shows the presence of S. hemolyticus in
pure culture from the blood of the heart, the lower lobe of the left
lung, pericardium and peritoneum. The right main bronchus contains
the same microorganism, B. influenzæ and a few staphylococci.
General serositis has been caused by hemolytic streptococci which in one
instance have entered the pleura from a subpleural abscess, and in the
other from the suppurating interstitial tissue of the lung. In one of
these cases the patient entered the hospital with symptoms suggestive of
acute peritonitis.
Bronchiectasis
Acute dilatation of the bronchi is a common result of the bronchitis of
influenza, and its frequent occurrence is an index of the severity of
the changes in the bronchial wall. In some instances the smaller bronchi
in well-localized areas are uniformly dilated; in other instances, large
cavities, several centimeters in diameter, are formed and all
transitions between the two extremes occur.
The occurrence of bronchiectasis following influenza is mentioned by
Leichtenstern[86]. He states that evidence of bronchiectasis can persist
for weeks or months and nevertheless end with complete restitution of
the lungs to normal. Lord[87] has described instances of bronchiectasis
occurring in association with infection by B. influenzæ and Boggs[88]
has recorded similar observations.
We have had abundant opportunity to observe early stages in the
production of bronchiectasis and to study the much discussed
pathogenesis of the condition.
The following figures show the predilection of bronchiectasis for the
left lung and for the lower lobes: Bronchiectasis occurred 30 times in
the left lung alone, 9 times in the right lung alone and 13 times in
both lungs, the total being 52. Among 30 instances in which the lesion
occurred only in the left lung, in 24 it was limited to the lower lobe,
and in 15 of these 24 instances to the base of the lower lobe. Among 9
instances in which dilatation of bronchi occurred only in the right
lung, it was limited to the lower lobe in 4 instances and to the base of
the lower lobe in 2 of these 4 instances.
When the lesion is limited to the base of the lower lobes small bronchi
with no recognizable cartilage in their wall are dilated to a diameter
of from 3 to 6 cm. and are distended with thick mucopurulent fluid. The
tenacious character of the bronchial contents and the action of gravity
doubtless have a part in the production of the dilatation. In several
instances dilatation of the bronchi was limited to the basal parts of
both upper and lower lobes.
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