Epidemic Respiratory Disease: The pneumonias and other infections of the repiratory tract accompanying influenza and measlesOpie, Eugene L. (Eugene Lindsay)
History
Epidemic Respiratory Disease: The pneumonias and other infections of the repiratory tract accompanying influenza and measles
Microscopic examination shows that bronchi, bronchioles, alveolar
ducts and the greater part of the infundibula are filled with
polynuclear leucocytes, whereas the alveoli surrounding these
structures contain fibrin. The walls of the small bronchi are
thickened and contain mononuclear cells; the adjacent alveolar walls
are similarly infiltrated and thickened and the fibrin within them
is undergoing organization, being invaded by plasma cells,
fibroblasts and newly formed blood vessels. In some sections
interstitial septa are distended by edema and contain fibrin in
abundance; in places the tissue contains polynuclear leucocytes
closely packed together. There are lymphatics greatly distended by
polynuclear leucocytes with some fibrin, lymphocytes and red blood
corpuscles.
=Autopsy 428.=—D. B., white, aged twenty-five, a farmer from
Oklahoma, had been in military service three weeks. Onset of illness
was on September 21, twenty-five days before death, with fever,
cough and mucopurulent expectoration. The patient was admitted with
the diagnosis of acute bilateral bronchitis. Four days later
bronchopneumonia was recognized, and subsequently there was otitis
media and empyema; 600 c.c. of thin, purulent fluid were aspirated
from the right chest three days before death.
=Anatomic Diagnosis.=—Unresolved bronchopneumonia; suppuration of
interstitial tissue of upper right and lower left lobes; purulent
bronchitis; fibrinopurulent pleurisy; thoracotomy wound at the base
of the right chest; collapse of both lungs; serofibrinous
pericarditis.
The left pleural cavity contains 550 c.c. of turbid seropurulent
fluid in which are numerous flakes of soft fibrin. The right pleural
cavity contains 150 c.c. of similar fluid. The mediastinum is
edematous. The pericardial cavity contains 50 c.c. of yellow fluid.
The right lung is moderately collapsed. In the upper and lower lobes
are small patches of red, lobular consolidation. The upper third of
the upper lobe is laxly consolidated and near its inner surface the
interstitial septa are thickened to from 1 to 1.5 mm. in width, and
at intervals occur bead-like swellings from which creamy purulent
fluid exudes upon the cut surface. In the left lung small patches of
gray consolidation occur throughout the lower lobe and here the
interstitial septa are thickened, beaded and contain purulent fluid.
Bacteriologic examination shows that the blood contains S.
hemolyticus; from the right lung and from the right main bronchus
hemolytic streptococci and B. influenzæ are grown.
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