Epidemic Respiratory Disease: The pneumonias and other infections of the repiratory tract accompanying influenza and measlesOpie, Eugene L. (Eugene Lindsay)
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Epidemic Respiratory Disease: The pneumonias and other infections of the repiratory tract accompanying influenza and measles
Microscopic examination shows the presence of peribronchiolar
patches of pneumonia in which there are few polynuclear leucocytes
and many lymphoid and plasma cells; the alveolar walls are thickened
and infiltrated with mononuclear cells. In some sections the tissue
is wholly consolidated and the site of advanced organizing
pneumonia. Interlobular septa and connective tissue about blood
vessels are thickened and cellular. Small bronchi have lost their
epithelial lining, their walls are thickened and there is
peribronchial organizing pneumonia. In some sections the lymphatics
are immensely dilated and distended with polynuclear leucocytes.
There is necrosis of the walls of the lymphatics and of the
polynuclear leucocytes within the lumen.
In the discussion of acute bronchopneumonia it has been shown that S.
hemolyticus is not infrequently a secondary invader of a pneumonic
lesion perhaps caused by pneumococci. With progress of the disease
hemolytic streptococci persist. In the autopsies with unresolved
pneumonia just described, hemolytic streptococci have found their way
into the lymphatics and produced suppurative lymphangitis with
inflammation of the interstitial septa of the lung.
CHAPTER V
SECONDARY INFECTION IN THE WARD TREATMENT OF MEASLES
JAMES C. SMALL, M.D.
A study of 979 cases of measles was made in the base hospitals of Camps
Funston and Pike from July to December, 1918, with the purpose of
establishing any existing relation between the prevalence of the
hemolytic streptococci and the incidence of the graver complications of
measles, especially the pneumonia following measles. The greater number
of these cases occurred at Camp Pike coincidently with the influenza
epidemic, so that the picture is modified during this period by a
summation of the after effects of the two diseases.
The work undertaken includes:
(a) Routine throat cultures on admission of all patients with measles.
(b) Separation and treatment in separate wards of the patients harboring
hemolytic streptococci and those free from such streptococci.
(c) Investigation of the bacteriology of all cases under treatment, by
weekly throat cultures during the period in the hospital.
(d) Bacteriologic study of the complications of measles during life and
at autopsy.
(e) Study of the throat bacteriology of men on duty in the camp, to
establish the prevalence of hemolytic streptococci and of B. influenzæ
in normal individuals.
The work is further divided into that done at Camp Funston during the
latter part of July and throughout August, and that done at Camp Pike
during September, October, November and December, 1918.
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