Epidemic Respiratory Disease: The pneumonias and other infections of the repiratory tract accompanying influenza and measlesOpie, Eugene L. (Eugene Lindsay)
History
Epidemic Respiratory Disease: The pneumonias and other infections of the repiratory tract accompanying influenza and measles
In Table LIX the cases of measles are grouped into fifteen day periods
according to their dates of onset and the pneumonias arising from each
group are tabulated. This tabulation shows very clearly that the
pneumonia complications developed in large part in patients with measles
entering the hospital during the influenza period, that is, late in
September and during the first half of October.
TABLE LIX
PATIENTS WITH MEASLES AND WITH SUBSEQUENT PNEUMONIA
═════════════════╤═════════════════╤═════════════════╤═════════════════
DATES │ TOTAL CASES OF │ TOTAL CASES │ OF PER CENT
│ MEASLES DURING │ PNEUMONIA FROM │ INCIDENCE OF
│ INTERVALS OF 15 │ SAME │ PNEUMONIAS
│ DAYS │ │
─────────────────┼────────┬────────┼────────┬────────┼────────┬────────
Sept. 11 to 30 │ 86│ 433│ 14│ 42│ 16.28│ 9.7%
Oct. 1 to 15 │ 347│ „ │ 28│ „ │ 8.07│ „
─────────────────┼────────┼────────┼────────┼────────┼────────┼────────
Oct. 16 to 31 │ 270│ 434│ 8│ 14│ 2.96│ 3.2%
Nov. 1 to 15 │ 91│ „ │ 2│ „ │ 2.2│ „
Nov. 16 to 30 │ 56│ „ │ 4│ „ │ 7.15│ „
Dec. 1 to 15 │ 17│ „ │ 0│ „ │
─────────────────┴────────┴────────┴────────┴────────┴─────────────────
The high incidence of pneumonia among measles patients coming into the
hospital prior to, with, or immediately following the height of the
influenza epidemic is very striking. It so happens that half of the
total number of measles cases considered, date their onsets prior to
October 15. From the 433 cases included in this first half, 42 cases of
pneumonia arose, while from the 434 cases arising during the two months
following October 15, only 14 or one-third as many cases of pneumonia
developed. These figures very strongly suggest that influenza played a
large part in the production of the pneumonia with measles in this group
of cases.
Again the 9.7 per cent incidence of pneumonia in the first half of cases
considered, approaches the 12 per cent incidence of pneumonia following
influenza observed in the epidemic at Camp Pike, while the incidence of
3.2 per cent in the second half of the cases conforms more nearly to
figures for pneumonia following measles in the army prior to the
pandemic of influenza.
It has been shown that the prevalence of B. influenzæ at Camp Pike
increased with the passing of the wave of influenza (p. 40) and that
this increase applied to the measles admissions. For a time the
separation of measles patients carrying B. influenzæ as identified by
throat culture on admission, from those free from it, was practiced. All
cases were then followed up by weekly throat cultures, and cases in
negative wards on being identified as positives were transferred.
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