Epidemic Respiratory Disease: The pneumonias and other infections of the repiratory tract accompanying influenza and measlesOpie, Eugene L. (Eugene Lindsay)
History
Epidemic Respiratory Disease: The pneumonias and other infections of the repiratory tract accompanying influenza and measles
Acute │ │ │ │ │ │ │
pleurisy │ 2│ 1│ 0│ 3│ │ │
Erysipelas of│ │ │ │ │ │ │
face │ 0│ 1│ 0│ 1│ │ │
Epidemic │ │ │ │ │ │ │
meningitis │ 0│ 1│ 0│ 1│ │ │
─────────────┴──────────┴─────────┴────────┴──────┴─────┴──────────┴─────────
Note.—The percentages of incidence of pneumonia and otitis media in the
“carrier” and “noncarrier” groups are at direct variance. It would appear
from these findings that streptococci very readily invade the middle ear from
the throat and set up grave disorders. The invasion of the lung from the
throat occurs with less frequency. Hemolytic streptococci perhaps never
initiate the pneumonic processes and can be regarded as more or less
accidental secondary invaders.
The relation of these pneumonias following measles, to the influenza
epidemic has been discussed. The time relations between the onsets of
measles and that of the subsequent pneumonia vary widely. There appears
to be nothing constant in the length of time between the onset of
measles and that of the pneumonia. In 30 of the cases this period is
less than ten days; in the remaining 26 cases, it ranges from ten to
thirty-two days (Chart 4).
In the ward treatment of these cases of pneumonia, they were divided
into three groups according to their clinical characters and according
to the results of throat and sputum cultures.
(_a_) Streptococcus pneumonias 9 cases
(_b_) Pneumonia with hemolytic streptococci in the throat
without symptoms referable to the streptococcus 13 cases
(_c_) Pneumococcus pneumonias not carrying hemolytic
streptococci 34 cases
The streptococcus-free cases were treated in a separate ward. Cases were
admitted to this ward directly from the “clean” measles wards, but only
after a throat culture taken prior to their transfer had been negative
for the hemolytic streptococcus.
The other two groups were treated together in another ward, but in
strictly separate compartments of it. This precaution was carried out on
the assumption that patients with an acute streptococcus pneumonia were
real sources of danger in the ward because of a heightened virulence of
the organism causing the grave symptoms. The pneumonias subsequently
developing hemolytic streptococci in their throats, without their
presence modifying the course of the pneumonia, came to be regarded as
being in the same class with uncomplicated cases of measles carrying
hemolytic streptococci, in so far as their being potential sources of
danger in a ward is concerned.
[Illustration:
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