Epidemic Respiratory Disease: The pneumonias and other infections of the repiratory tract accompanying influenza and measlesOpie, Eugene L. (Eugene Lindsay)
History
Epidemic Respiratory Disease: The pneumonias and other infections of the repiratory tract accompanying influenza and measles
One hundred and eleven consecutive cases in which careful clinical and
bacteriologic studies were made form the basis of the material
presented. Of these cases, 38 came to necropsy so that ample opportunity
was presented to correlate the clinical and bacteriologic studies made
during life with the pathology and bacteriology at necropsy. It has
seemed advisable to group the cases primarily on an etiologic basis with
secondary division according to clinical features in so far as this can
be done. Bacteriologic studies showed that at the time of onset these
pneumonias were either pneumococcus pneumonias or mixed pneumococcus and
influenza bacillus pneumonias in nearly all instances. Certain of these
cases later became complicated by a superimposed hemolytic streptococcus
or a staphylococcus infection. In a few instances hemolytic
streptococcus pneumonia directly followed influenza without an
intervening pneumococcus infection. B. influenzæ was present in varying
numbers in nearly all cases. In only 2 instances however, was it found
unassociated with pneumococci or hemolytic streptococci, once alone and
once with S. viridans.
Clinically the cases fell into four main groups: (1) Lobar pneumonia;
(2) lobar pneumonia with purulent bronchitis; (3) bronchopneumonia
(pneumococcus); (4) bronchopneumonia (streptococcus). It should be borne
in mind, however, that the picture was a complex one and that correct
clinical interpretation was not always possible, since many cases did
not conform sharply to any one type and superimposed infections during
the course of the disease often modified the picture.
=Pneumococcus Pneumonia Following Influenza.=—Bacteriologic examination
of selected and washed specimens of sputum coughed from the lungs at
time of onset of pneumonia showed the various immunologic types of
pneumococcus to be present in 105 cases. The incidence of the different
types is shown in Table XIV.
TABLE XIV
TYPES OF PNEUMOCOCCUS IN 105 CASES OF PNEUMOCOCCUS PNEUMONIA FOLLOWING
INFLUENZA
═══════════════════════╤═════════╤═════════════════╤═════════╤═════════
│ LOBAR │BRONCHOPNEUMONIA │ TOTAL │PER CENT
│PNEUMONIA│ │ │
───────────────────────┼─────────┼─────────────────┼─────────┼─────────
Pneumococcus, Type I │ 8│ 0│ 8│ 7.6
Pneumococcus, Type II │ 3│ 1│ 4│ 3.8
Pneumococcus, II atyp. │ 12│ 7│ 9│ 18.1
Pneumococcus, Type III │ 3│ 3│ 6│ 5.7
Pneumococcus, Group IV │ 32│ 36│ 68│ 64.8
───────────────────────┴─────────┴─────────────────┴─────────┴─────────
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