_All told._ _Per 10,000 inhabitants._ 1868 597 1·9 1869 275 0·9 1870 973 3·0 1871 7,912 24·2 1872 1,786 5·4 1873 113 0·3 In the first quarter of the year 1871 some 2,400 persons succumbed to small-pox in London, in the second quarter 3,241, in the third quarter 1,255, and in the fourth quarter 980. The epidemic broke out in the East End of London in the fortieth week of the year 1870, i.e. in the first part of October; the number of deaths caused by it there was 40, and by the end of the year this number had increased to 110. Of the English counties, those along the north-east coast were most severely attacked; for example, Durham and Northumberland, where the number of deaths caused by the disease was 45·0 and 29·8, respectively, per 10,000 inhabitants. In the cities of Sunderland and Newcastle-on-Tyne, located in these counties, the number of deaths per 10,000 inhabitants in the year 1871 was 86·0 and 54·1 respectively. There was a very large number of deaths in London (24·2 per 10,000 inhabitants), and the counties bordering on London (Middlesex and Essex) also suffered severely (9·3 and 8·0 respectively); next in order come the counties of Monmouthshire and Lancashire with 14·8 and 11·9 respectively. The high mortality in Lancashire was due only to the city of Lancaster, where there were no less than 38·8 deaths per 10,000 inhabitants; in the rest of the county the number of deaths per 10,000 inhabitants was only 6·3. In Scotland and Ireland the number of deaths caused by small-pox was: _All told._ _Per 10,000 inhabitants._ _Scotland._ _Ireland._ _Scotland._ _Ireland._ 1869 64 20 0·2 0·04 1870 114 32 0·3 0·1 1871 1,442 665 4·3 1·2 1872 2,448 3,248 7·2 6·2 1873 1,126 504 3·3 0·9 1874 1,246 569 3·6 1·1 1875 76 535 0·2 1·0 Small-pox spread very slowly to Scotland and Ireland; whereas in England the maximum number of persons died in the year 1871, in Scotland and Ireland the maximum number of deaths occurred in the year 1872. Both countries, moreover, were less severely attacked than England. _(g) Denmark, Norway, Sweden, Finland, and Russia_