Epitome of the Pharmacopeia of the United States and the National Formulary: With CommentsHewlett, Albion Walter
Science
Epitome of the Pharmacopeia of the United States and the National Formulary: With Comments
Hewlett, Albion Walter
Medicine -- Formulae, receipts, prescriptions; Pharmacopoeias -- United States
Light, white, odorless, very bitter silky needles. Soluble in water
(1:40), and very soluble in alcohol (1:0.9).
ACTION AND USES: Superfluous; see =Quininae Hydrochloridum=.
DOSAGE: Tonic, 0.1 Gm. or 1-1/2 grains (U.S.P.);
antimalarial, at least 1 Gm. or 15 grains, daily (U.S.P.).
=*Quininae Hydrochloridum (Quin. Hydrochl.), Quinine Hydrochloride,
U.S.P.= (Quinine Chloride).
White, odorless, very bitter, silky needles. Soluble in water
(1:18) and very soluble in alcohol (1:0.8).
ACTION AND USES: Has the action of other quinine salts;
frequently preferred to the sulphate, because neutral and
more soluble.
DOSAGE: Tonic, 0.1 Gm. or 1-1/2 grains (U.S.P.);
antimalarial, at least 1 Gm. or 15 grains daily (U.S.P.).
_Syrupus Phosphatum cum Quinina et Strychnina (Syr. Phosphat. c. Quin.
et Strych.), Syrup of Phosphates with Quinine and Strychnine, N.F._
(Syrupus Hydrochlorophosphatum, N.F. III, Compound Syrup of
Hydrochlorophosphates).--Quinine hydrochloride (0.44%), strychnine
nitrate (0.014%), compound solution of phosphates (50%) in glycerin and
syrup.
DOSAGE: 4 Cc. or 1 fluidrachm (N.F.)
=Quininae Hypophosphis (Quin. Hypophos.), Quinine Hypophosphite, N.F.=
Fine, white, odorless crystals, with a very bitter taste.
ACTION AND USES: Superfluous quinine salt.
DOSAGE: Tonic, 0.1 Gm. or 1-1/2 grains (N.F.); antimalarial,
1 Gm. or 15 grains daily (N.F.)
=Quininae Salicylas (Quin. Salicyl.), Quinine Salicylate, U.S.P.=
Colorless (often becoming pinkish), odorless, bitter needles.
Soluble in alcohol (1:14) and in glycerin (1:13). Only slightly
soluble in water.
ACTION AND USES: Superfluous; see Quininae Hydrochloridum.
The quantity of salicylate in a dose is usually
too small to be effective.
DOSAGE: Tonic, 0.1 Gm. or 1-1/2 grains (U.S.P.);
antimalarial, at least 1 Gm. or 15 grains daily (U.S.P.)
=*Quininae Sulphas (Quin. Sulph.), Quinine Sulphate, U.S.P.=
White, odorless, very bitter, efflorescent crystals. Slightly
soluble in water (1:725) and in alcohol (1:107).
ACTION AND USES: The most commonly used quinine salt
but inferior to the hydrochloride, the dihydrochloride and
quinine and urea hydrochloride where a soluble salt is
desired, and to the alkaloid or the tannate where an
insoluble one is needed.
DOSAGE: Tonic, 0.1 Gm. or 1-1/2 grains (U.S.P.);
antimalarial, at least 1 Gm. or 15 grains daily (U.S.P.).
_Elixir Cinchonae Alkaloidorum (Elix. Cinchon. Alk.), Elixir of Cinchona
Alkaloids, N.F. (Elixir Cinchonae, N.F._ III, Elixir Calisaya,
Alkaloidal).--Quinine sulphate (0.2%), cinchonidine sulphate (0.1%),
cinchonine sulphate (0.1%), compound tincture of cudbear and aromatic
elixir. Absolute alcohol content about 21 per cent.
USES: Imitation of cinchona, minus the tannin. No
advantage over quinine.
DOSAGE: 8 Cc. or 2 fluidrachms (N.F.).
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