Epitome of the Pharmacopeia of the United States and the National Formulary: With CommentsHewlett, Albion Walter
Science
Epitome of the Pharmacopeia of the United States and the National Formulary: With Comments
Hewlett, Albion Walter
Medicine -- Formulae, receipts, prescriptions; Pharmacopoeias -- United States
ACTION AND USES: Strophanthus and tincture of strophanthus
have properties similar to those of the glucoside
strophanthin. The absorption of strophanthus from the
alimentary canal is so variable that administration by
mouth is not advisable.
DOSAGE: 0.06 Gm. or 1 grain (U.S.P.).
_*Tinctura Strophanthi (Tr. Strophanth.), Tincture of Strophanthus,
U.S.P._ (Strophanthi Tinctura, P.I.).--Strophanthus (10%) with the oil
removed. Biologically assayed by producing death in frogs. Absolute
alcohol content about 92 per cent.
DOSAGE: 0.5 Cc. or 8 minims (U.S.P.). Physicians
who prescribe it should specify the biologically assayed
preparation.
=Strychnina (Strych.), Strychnine, U.S.P.=--An alkaloid obtained from
nux vomica.
Colorless, odorless crystals or white powder. Extremely bitter in
very dilute solutions. Very slightly soluble in water (1:6420) and
slightly soluble in alcohol (1:136).
ACTION AND USES: Stimulates the reflex activity of the
spinal cord, but produces little or no effect on the higher
nervous centers; is also used as a bitter tonic, generally in
the form of a preparation of nux vomica.
As strychnine is so slightly soluble, it is generally prescribed as
one of its salts. Of these, the nitrate meets every need.
DOSAGE: 0.0015 Gm. or 1/40 grain (U.S.P.).
_Elixir Pepsini, Bismuthi et Strychninae (Elix. Pepsin. Bism. et
Strych.), Elixir of Pepsin, Bismuth and Strychnine, N.F._--Strychnine
(0.0175%), tartaric acid, and elixir of pepsin and bismuth. Absolute
alcohol content about 10 per cent.
USES: An irrational preparation.
DOSAGE: 4 Cc. or 1 fluidrachm (N.F.).
_Pilulae Antidyspepticae (Pil. Antidyspep.), Antidyspeptic Pills,
N.F._--Each pill contains strychnine (0.0016 Gm., or 1/40 grain), ipecac
and pilular extract of belladonna leaves (each 0.0065 Gm., or 1/10
grain), mass of mercury, and compound extract of colocynth (each 0.13
Gm., or 2 grains).
USES: An objectionably named and misdirected mixture.
DOSAGE: 1 pill (N.F.).
=Strychninae Acetas, Strychnine Acetate.=
_Liquor Strychninae Acetatis (Liq. Strych. Acet.), Solution of
Strychnine Acetate, N.F._ (Hall's Solution of Strychnine).--Strychnine
acetate (about 0.209%), alcohol, compound tincture of cardamom and
water. Absolute alcohol content about 23 per cent.
USES: Superfluous strychnine solution.
DOSAGE: 0.6 Cc. or 10 minims (U.S.P.).
=Strychninae Glycerophosphas (Strych. Glycerophos.), Strychnine
Glycerophosphate, N.F.= (Strychnine Glycerinophosphate).
White, odorless crystals or powder, with a taste at first sweet,
afterward intensely bitter. Slightly soluble in water (1:350), and
in alcohol (1:310).
ACTION AND USES: Superfluous strychnine salt.
DOSAGE: 0.0015 Gm. or 1/40 grain (N.F.).
=*Strychninae Nitras (Strych. Nit.), Strychnine Nitrate, U.S.P.=
Colorless, odorless crystals or white powder. Soluble in water
(1:42) and somewhat less soluble in alcohol.
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