If the lips of a polype be cut transversely, and placed so that the cut part of the skin may lie directly before the microscope, the skin throughout its whole thickness will be found to consist of an infinite number of these grains. To know whether the inside of the stomach was formed of similar grains, several of them have been laid open and examined by the microscope; the interior surface was then found to consist of an immense number of them, being as it were more shagreened than the exterior one, and less transparent. The grains are not strongly united to each other, but may be separated without much trouble. Plate XXIII. A. Fig. 10, represents a piece of skin thus laid open. To examine these particulars further, a piece of skin a, Fig. 9, was laid in a few drops of water, on a piece of glass before the microscope, and some of the grains were separated from it, as at b c d, by pressing them with the point of a pin; in endeavouring to open them, they spread themselves into all parts of the water, and at last remained in heaps, as at e and f. If a polype be carefully placed before the microscope, without wounding it, you will seldom be disappointed in seeing some of these grains detach themselves from the superficies thereof, and that even in the most healthy. But if the grains separate themselves in large quantities, it is the symptom of a very dangerous disorder; the surface of the polype thus attacked becomes more and more irregular, and is no longer well terminated and defined as before. The grains fall off on all sides, the body and arms contract and dilate, it becomes of a white shining colour, loses its form as at a, Fig. 4, and then dissolves into a heap of grains, as at b, Fig. 5. The progress of this disorder is most easily observed in the hydra viridis. A very attentive and accurate examination shews that the skin is formed of a kind of glareous substance, a species of gum, which fills up the intervals between the grains, in which they are lodged, and by which they are attached, though weakly, together. It has been already observed, that it is to these grains that it owes its shagreen-like appearance; it is from them also that it derives its colour; for, when they are separated from the polype, they are the same colour with it, whereas the glareous matter is without any distinguishing colour. The construction of the polype seems then to be confined to these glandular grains, to the viscous matter, and the invisible fibres which act upon the glareous substance.