Operative measures, such as punctate and linear scarification, electrolysis and excision, are occasionally practised, but the results are rarely satisfactory and permanent; not infrequently, indeed, renewed activity in the progress of the growth is noted to follow. The _x_-ray can be tried with some hope of improvement. The administration of thyroid has been thought to have a possible influence in some instances. #Fibroma.# (_Synonyms:_ Molluscum Fibrosum; Fibroma Molluscum.) #What do you understand by fibroma?# Fibroma is a connective-tissue new growth characterized by one or more sessile or pedunculated, pea- to egg-sized or larger, soft or firm, rounded, painless tumors, seated beneath and in the skin. #Describe the clinical appearances of fibroma.# The growth may be single, in which case it is apt to be pedunculated or pendulous, and attain considerable dimensions; as a result of weight or pressure surface-ulceration may occur. Or, as commonly met with, the lesions are numerous, scattered over large surface, and vary in size from a pea to a cherry; the overlying skin being normal, pinkish or reddish, loose, stretched, hypertrophied or atrophied. The tumors are painless. The general health is not involved. [Illustration: Fig. 41. Fibroma. (_After Octerlony._)] #What is the course of fibroma?# Chronic and persistent. #What is the etiology of fibroma?# The cause is not known. Heredity is often noted. The affection is not common. #State the pathology of fibroma.# The growths are variously thought to have their origin in the connective tissue of the corium, or in that of the walls of the hair-sac, or in the connective-tissue framework of the fatty tissue. Recent tumors are composed of gelatinous, newly-formed connective tissue, and the older growths of a dense, firmly-packed, fibrous tissue. #From what growths is fibroma to be differentiated?# From molluscum contagiosum, neuroma and lipoma; the first is differentiated by its central aperture or depression, neuroma by its painfulness, and lipoma by its lobulated character and soft feel. #Give the prognosis of fibroma.# The disease is persistent, and irresponsive to all treatment save operative measures. #What is the treatment of fibroma?# Treatment consists, when desired and practicable, in the removal of the growths by the knife, or in large and pedunculated tumors by the ligature or by the galvano-cautery. #Neuroma.# #Describe neuroma.# Neuroma of the skin is an exceedingly rare disease, characterized by the formation of variously-sized, usually numerous, firm, immovable and elastic fibrous tubercles containing new nerve-elements, and accompanied by violent, paroxysmal pain. Their growth is slow and usually progressive. Later they are painful upon pressure. They are limited to one region.