The _papular_ eruption is observed in conjunction with the erythematous manifestation, or it occurs alone. The lesions are but slightly elevated, and seem to partake of the nature of both macules and papules. They are usually discrete, and rarely abundant; they may become decked with a film-like scale, and at the various points of junction of skin and mucous membrane, and in the folds, they become abraded and macerated, developing into _moist papules_. The _bullous_ eruption consists of variously-sized, more or less purulent blebs, and is usually met with at or immediately following birth. It is most abundant about the hands and feet. Macules and papules are often interspersed. There may be superficial or deep ulceration underlying the bullae. #What other symptoms in addition to the cutaneous manifestations are noted in hereditary syphilis in the newborn?# Mucous patches, and sometimes ulcers, in the mouth and throat; hoarseness, as shown by the peculiar cry, and indicating involvement of the larynx; snuffles, a sallow and dirty appearance of the skin, loss of flesh and often a shriveled or senile look. #What is the pathology of cutaneous syphilis?# The syphilitic deposit consists of round-cell infiltration. The mucous layer, the corium, and in the deep lesions the subcutaneous connective tissues also, are involved in the process. The infiltration disappears by absorption or ulceration. The factor now believed to be responsible for the disease and the pathological changes is the Spirochaeta pallida, discovered by Schaudinn and Hoffmann, and usually found in numbers in the tissues. #Give the prognosis of cutaneous syphilis.# In _acquired syphilis_, favorable; sooner or later, unless the whole system is so profoundly affected by the syphilitic poison that a fatal ending ensues, the cutaneous manifestations disappear, either spontaneously or as the result of treatment. The earlier eruptions will often pass away without medication, but treatment is of material aid in moderating their severity and hastening their disappearance, and is to be looked upon as essential; in the late syphilodermata treatment is indispensable. In the large pustular, the tubercular and gummatous lesions, considerable destruction of tissue may take place, and in consequence scarring result. Ill-health from any cause predisposes to a relapse, and also adds to the gravity of the case. In _hereditary infantile syphilis_, the prognosis is always uncertain: the more distant from the time of birth the manifestations appear the more favorable usually is the outcome. #How is cutaneous syphilis to be treated?# Always with constitutional remedies; and in the graver eruptions, and especially in those more or less limited, with local applications also. #What constitutional and local remedies are commonly employed in cutaneous syphilis?# _Constitutional Remedies._--Mercury and potassium iodide; tonics and nutrients are necessary in some cases.