The constitutional treatment, beyond a regulation of the diet, is to be based upon a correct appreciation of the etiological factors in the individual case. There are no special remedies. Iron, cod-liver oil, tonics, ergot, alkalies, saline laxatives, and similar drugs are to be variously prescribed. #What is the external treatment?# In many respects, both as to the preliminary measures and remedies, essentially the same as that employed in the treatment of simple acne (_q. v._). The _x_-ray treatment is not so efficient in this disease, however, as in acne. In addition to the treatment there found, several other applications deserve mention:-- In many cases _Vleminckx's solution_[C] is valuable, applied diluted with one to ten parts of water. Also, a mucilaginous paste containing sulphur:-- [Rx] Mucilag. acaciae, ..................... f[dram]iij Glycerinae, ........................... f[dram]ij Sulphur, praecip., .................... [dram]iij. M. [Footnote C: [Rx] Calcis, .............................. [Oz]ss Sulph. sublimat., .................... [Oz]j Aquae, ................................ [Oz]x. To be boiled down to [Oz]vj and filtered.] Or a similar paste with the glycerine in the foregoing replaced with ichthyol may be used. #In what manner are the dilated bloodvessels and connective-tissue hypertrophy to be treated?# The enlarged capillaries are to be destroyed by incision or by electrolysis. Properly managed the vessels may be thus destroyed, but unless the predisposing causes have disappeared or have been remedied, a new growth may take place. If the knife is employed, the vessels are either slit in their length or cut transversely at several points. The method by electrolysis is the same as used in the removal of superfluous hair (_q. v._).; the needle may, if the vessel is short, be inserted along its calibre, or if long, may be inserted at several points in its length. Excessive connective-tissue growth, exceptionally met with, is to be treated by ablation with the scissors or knife. #Acne Varioliformis.# (_Synonyms:_ Acne Frontalis; Acne Rodens; Acne Necrotica; Lupoid Acne; Necrotic Granuloma.) #Describe acne varioliformis.#