Occasionally a sycosiform eruption, usually of the side of the bearded region, leaves behind a smooth or keloidal scar, the disease gradually extending--_ulerythema sycosiforme_ (lupoid sycosis). An inflammation of the hair-follicles of the scalp apparently sycosiform in character, occurring as discrete or aggregated lesions, is sometimes observed, the follicles being destroyed and atrophy or slight scarring resulting--_folliculitis decalvans_. #Does conspicuous hair loss occur in sycosis?# Ordinarily not; the hairs are, especially at first, usually firmly seated, but in those cases in which suppuration is active, and has involved the follicles, they may, as a rule, be easily extracted. In some cases destruction of the follicles ensues and slight scarring and permanent hair loss result. #State the character of the subjective symptoms.# Pain and itching and a sense of burning, variable as to degree, may be present. #What is the course of the disease?# Essentially chronic, the inflammatory action being of a subacute or sluggish character, with acute exacerbations. #State the causes of sycosis.# Upon the upper lip it may have its origin in a nasal catarrh. Entrance into the follicles of pyogenic micrococci is now regarded as the essential factor. This view being accepted, carries with it the possibility of contagiousness. It is seen in the male sex only, usually in those between the ages of twenty-five and fifty; and is met with in those in good and bad health, and among rich and poor. It is comparatively infrequent. #What is the pathology of sycosis?# The disease is primarily a perifolliculitis, the follicle and its sheath subsequently becoming involved in the inflammatory process. #How would you distinguish sycosis from eczema?# Eczema is rarely sharply limited to the bearded region, but is apt to involve other parts of the face; moreover, the lesions are usually confluent, and there is either an oozing, red crusted surface, or it is dry and scaly. #How would you exclude tinea sycosis in the diagnosis?# In tinea sycosis, or ringworm sycosis, the history of the case is different. The parts are distinctly lumpy and nodular; the hairs are soon involved and become dry, brittle, loose, and fall out, or they may be readily extracted. The superficial type of ringworm sycosis is readily distinguished by the ring-like character of the patches. In doubtful cases, microscopic examination of the hairs may be resorted to. #Give the prognosis of sycosis.# The disease is curable, but almost invariably obstinate and rebellious to treatment. The duration, extent, and character of the inflammatory process must all be considered. An expression of an opinion as to the length of time required for a cure should always be guarded. Ulerythema sycosiforme is extremely obstinate. Folliculitis decalvans is also rebellious. #How is sycosis to be treated?# Mainly, and often exclusively, by external applications.