A large portion of the physicians in the early days of the Colony were Puritan ministers who had studied medicine in England in anticipation of removal to New England, as a hasty preparation for such necessities as might arise. Each practised in his own flock and Cotton Mather in his _Magnalia_ (Book III, Chap. 26), speaks of this union of the two professions as an "Angelical Conjunction." When Rev. Michael Wigglesworth died in 1705, his weeping parishioners in the town of Malden, erected a stone to mark his grave and on it may still be read the words "Here lies intered in silent grave below Maulden's physician for soul and body two." In colonial times there was little regulation of medical practice, although an ineffective law was passed in 1649. Any one might come into a town and announce himself as a physician and if able to cure patients of their maladies, his success was assured. Several unfortunate failures, however, would seriously effect his standing. As a natural result quacks appeared and disappeared in all the larger towns. In the seventeenth century, and later, there were two classes of medical practitioners of which one prescribed vegetable substances only, together with a free use of the lancet, and followed the teachings of Galen, the Greek physician. The other school followed the doctrines of Paracelsus and prescribed for the most part mineral preparations, and oftentimes were styled "chemists." Of course there was bitter rivalry between the two schools, each maintaining so far as possible, a superstitious mystery concerning their profession. There were few regular graduates from any recognized medical school. Until after the Revolution most practitioners gained their scanty store of medical knowledge by studying with some family physician and in the homely school of experience. Dr. William Douglas, a young Scotchman, began to practice in Boston in 1716. In 1721 he wrote "we abound with Practitioners, though no other graduate than myself. We have fourteen Apothecary shops in Boston. All our Practitioners dispense their own medicines.... In general the physical practise in our colonies is so perniciously bad that excepting in surgery and in some very acute cases, it is better to let nature under a proper regimen take her course than to trust to the honesty and sagacity of the practitioner. Our American practitioners are so rash and officious that the saying in Ecclesiasticus may with much propriety be applied to them, 'He that sinneth before his Maker let him fall into the hands of the physician.'"[68] [68] 4 Mass. Hist. Colls., II, 164.