In regard to the 8th statement of Brown-Séquard, as to various morbid states of the skin, Romanes did not test this, because the facts which it alleges did not seem of a sufficiently definite character. These experiments of Brown-Séquard, and of those who have repeated them, may appear to give a brilliant experimental confirmation of the Lamarckian position; yet I think, if I were a Lamarckian, I should feel very uncomfortable to have the best evidence in support of the theory come from this source, because there are a number of facts in the results that make them appear as though they might, after all, be the outcome of a transmitted disease, as Weismann claims, rather than the inheritance of an acquired character. Until we know more of the pathology of epilepsy, it may be well not to lay too great emphasis on these experiments. It should not be overlooked that during the long time that the embryo is nourished in the uterus of the mother, there is ample opportunity given for the transmission of material, or possibly even of bacteria. If it should prove true that epilepsy is due to some substance present in the nervous system, such substances could get there during the uterine life of the embryo. Even if this were the case, it may be claimed that it does not give an explanation of the local reappearance of the disease in the offspring. But here also we must be on our guard, for it is possible that only certain regions of the body are susceptible to a given disease; and it has by no means been shown that the local defect itself is inherited, but only the disease. Romanes insists that a very special operation is necessary to bring about certain forms of transmission. It is well also to keep in mind the fact, that if this sort of effect is inherited, then we must be prepared to accept as a possibility that other kinds of injury to the parent may be transmitted to the offspring. It would be of great disadvantage to animals if they were to inherit the injuries that their parents have suffered in the course of their lives. In fact, we might expect to find many plants and animals born in a dreadful state of mutilation as a result of inheritances of this sort. Thus, while the Lamarckians try to show that, on their principle, characters for the good of the species may be acquired, they must also be prepared, if they accept this kind of evidence, to grant that immense harm may also result from its action. I do not urge this as an argument against the theory itself, but point it out simply as one of the consequences of the theory.