A few months after the paintings were finished for Marie de' Medici, a great sorrow came to the Rubens mansion. Isabella Brandt, his wife, died in the middle of the year 1626, leaving two sons, Albert and Nicholas, twelve and eight years of age. She was buried with much display in the Abbey Church of St. Michael, where she had been married,--in the same tomb with his mother and his brother Philip, and her husband dedicated a beautiful "Virgin and Child" to her memory. He wrote to a friend, sadly, in regard to her whom he had lost, as one "not having any of the vices of her sex. She was without bad temper or feminine frivolity, but was in every way good and honorable--in life loved on account of her virtues, and since her death universally bewailed by all. Such a loss seems to me worthy of sympathy, and because the true remedy for all evils is forgetfulness, the daughter of time, one must without doubt hope for relief; but I find the separation of grief for the departed from the memory of a person whom I ought to revere and honor whilst I live, to be very difficult." Partly to distract his mind from his grief, and partly to assist his own country, to which he was devotedly attached, to keep peace with the powers at war, which made Belgium their battle-ground, at the request of the Infanta Isabella he visited Holland on a diplomatic mission, and, a little later, Spain and England. The King of Spain had already ennobled Rubens. "Regard being had to the great renown which he has merited and acquired by excellence in the art of painting, and rare experience in the same, as also by the knowledge which he has of histories and languages, and other fine qualities and parts which he possesses, and which render him worthy of our royal favor, we have granted and do grant to the said Peter Paul Rubens and his children and posterity, male and female, the said title and degree of nobility." In consequence of this, Isabella had made him "gentleman of her household." In this his second visit to Spain, he is said to have painted forty pictures in nine months. Rubens and Velasquez became intimate friends, although the former was fifty-one, and the latter twenty-eight. A little later he was sent by Philip IV. of Spain, who had appointed Rubens secretary to his privy council, on a mission to England. Here he was discovered by a courtier, one morning, busy at his painting. "Ho!" said the courtier, "does his Most Catholic Majesty's representative amuse himself with painting?" "No," answered Rubens, "the artist sometimes amuses himself with diplomacy."