Dubois tells of two brothers who were bitten by a mad dog. One had to leave at once for America, and thought no more about it. When he returned twenty years afterwards, he heard through some thoughtless person that his brother had died of hydrophobia, and was so agitated by the news that he fell ill and died, showing all the symptoms of rabies. Medical works are full of instances of persons bitten by dogs, who only developed hydrophobic symptoms after being incautiously told that the dog was mad. It is often impossible even for the physician to distinguish hypochondriac hydrophobia from true rabies; even the manner of death is no guide, for tetanic contractions of the respiratory organs appear also in hypochondriac hydrophobia. The physician can often save these patients, if he knows how to exert authority and to make use of means to convince the sufferer that he has nothing to fear. The story is told of a physician who was called to a female patient infected with actual rabies, after his colleagues had declared that she was incurable. He examined her attentively, then kissed her on the mouth to prove to her that she was not hydrophobic. The patient recovered. More especially during epidemics does fear play havoc. From the most remote antiquity physicians have observed that the timid die more easily. Giorgio Baglivi, in his celebrated book 'Praxis Medica,’[34] describing the effects of an earthquake which took place in Rome in 1703, says that although not a single person was killed, several died of fever through fear, many women miscarried, and all bedridden invalids grew worse. Larrey had already noticed that on the fields of battle and in the lazarets soldiers belonging to the conquered army succumbed more easily to their wounds, while the victors more speedily recovered. This was confirmed in the war of 1870. [34] Baglivi: _Praxis Medica_, liber. i, cap. xiv. s. 5. Fear alone may develop all the symptoms of a pestilential malady, even when the epidemic causes are totally wanting. Just recently, in one of his works on hysteria and hypochondria, Jolly relates the case of a patient of his, a lady in Strasburg, who received the news of the death of a relative from cholera in a distant country. She was very much frightened, and imagined that she herself was attacked by it. She lost her appetite and suffered for eight days from violent attacks of diarrhœa, and only after convincing her that there was not a single case of cholera in Strasburg, and that she was a prey to her own imagination, was it possible to allay the serious intestinal disturbances produced by fear. As soon as a report of cholera spreads through a town, all hypochondriacs feel worse.