It was customary on every Friday in March for people to go up to S. Miniato to obtain pardon for their sins, and Luisa’s brother Leone Strozzi, Prior of Capua, Giuliano Salviati and other young nobles, stood watching the ladies come out of the church. As Luisa passed Giuliano made some insolent remarks, so the Prior said: “Giuliano, you perhaps do not know that she is my sister;” whereupon Giuliano repeated his insulting words. On the following night, as Salviati was returning on horseback from the Palazzo Medici, he was assaulted by three strangers and wounded in the face and on the leg, so that he was lame ever after. Duke Alessandro was furious, and gave orders that the assassins must be discovered. Suspicion, of course, fell on the Strozzi. Piero, Leone the Prior, and two of their friends were arrested, and there was a question of putting them to the torture; but Clement VII. interfered, and ordered that nothing more should be done. Piero Strozzi and his brothers, knowing their lives were in danger, took horse and went to Rome. Meanwhile Luisa, who had remained in Florence with her husband, supped joyously one night, as the old chronicler Segni reports, with her sister Maria, wife of Lorenzo Ridolfi. A few hours afterwards she died in excruciating agony, and her body turned black. Her relations insisted on a post mortem examination, and the doctors declared that she had died from the effect of some virulent poison. Varchi more than hints that her own family were the culprits, out of fear that the Duke, “by means of some treachery or fraud, purposed to stain the honour of their family in the person of Luisa.” But Segni and others agree that, having repulsed the Duke Alessandro, as she had done Salviati, his infamous wife poisoned her by the Duke’s orders. Not long after the death of the beautiful Luisa, her father and her brothers were declared rebels and outlaws by the Duke Alessandro. The sentence was confirmed by his successor Cosimo I. because Lorenzino de’ Medici, after he had murdered his cousin the Duke Alessandro, fled to Venice where Filippo Strozzi hailed him as a second Brutus.