s. d. Bleeding----Daughter . . . . . . . 1 0 A febrifuge Mixture . . . . . . . 2 4 Bleeding----Self . . . . . . . . . 1 0 A Cordial Mixture . . . . . . . . 2 4 A Diuretic Tincture . . . . . . . 1 6 Two Opening Draughts . . . . . . . 2 0 The Mixture repd . . . . . . . . . 2 4 Bleeding----Daughter . . . . . . . 1 0 Two Opening Draughts . . . . . . . 2 0 -------- L0 15 6 The item "Bleeding----self" is a trifle ambiguous, but probably it was the parent and not the doctor upon whom the operation was performed! Inoculation has already been referred to, but I may here state that the first account I have seen of professional inoculation for the smallpox in Royston is the announcement in the year 1773 of--"George Hatton, surgeon, apothecary and man-mid-wife in Royston, who, with the advice of his friends and the many patients whom he has inoculated, begs leave to acquaint the public that he will wait upon any person or family within 6 or 7 miles from Royston, and inoculate them for half-a-guinea each person, medicines and attendances included, and, that the poor may have the benefit of his practice, a proper allowance will be made them and diligent attendance given." Bills of the same period show that the charge for this species of inoculation "when a quantity was taken," as in the parish bills, was 2s. or 2s. 6d. each person. The advantage claimed for spreading the disease of small-pox out of the rates by means of inoculation was that if you had it as the result of inoculation only one person in 300 died, but if you had small-pox by infection, eight out of every hundred died. It may be of interest to add as a general fact upon health and diseases, that in 1792, out of 20,000 burials the following were the proportions of deaths from the leading diseases:--Consumption 5,255, convulsions {81} 4,646, dropsy 3,018, fevers 2,203, small-pox 1,568, measles 450, "teeth" 419. The deaths under two years of age were 6,542, or one-third of the whole! The classification was not so exact in those days as it would be now, but the race has improved a little in regard to infantile mortality and consumption.