His larger interest in the diocese probably had its beginning when in 1908 as a member of the Social Service Commission he visited the Hocking Valley, and was shocked by the abominable living conditions of the miners and the almost intolerable injustice of their economic circumstances. His interest, thus fired, increased with the years until he came to be depended upon in every sphere of diocesan life, serving on the Standing Committee, the Bishop and Chapter, the Board of Strategy and Finance, and in practically every other committee and department of importance. He was most insistent on maintaining the missionary program, which he held to be the very heart-beat of the life of the Church. Even during depressions, Christ Church never lowered its missionary giving of $24,000, and one year voted $3000.00 from its parish budget to make up a deficit in the missionary budget because as he said "We have failed to educate the people." His thorough knowledge and good judgment were of infinite value to a succession of bishops. On the occasion of Mr. Nelson's Fortieth Anniversary, the present Bishop, Henry Wise Hobson said, "In all parts of the Diocese I have heard clergy and lay people say such words as these: 'The spirit of honesty, courage, fellowship, and service which has grown up in the life of our Diocese is primarily the result of the influence of Frank Nelson, whose own spirit has been a contagious force in our midst.'" Others who have observed the remarkable growth and increasing strength of this Diocese say that its present vitality has been generated, not by numbers, nor by wealth, but by the passionate spirit of certain recognizable characters of whom Frank Nelson was easily the leader. During Bishop Reese's long illness, Mr. Nelson largely conducted the business of the Diocese, and for a man with such positive convictions, he was extremely fair in presiding at the Convention. He leaned over backward to be just, and did not silence even those who brought up petty reasons for disagreement on the subjects under debate.